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R01 DK110276

Funded outputs count: 21
Funder award ID: R01 DK110276
OpenAlex ID: G7104924317
Heterogeneity in the coordination of delta cells with beta cells is driven by both paracrine signals and low-density Cx36 gap junctions
2025 · Mohammad S. Pourhosseinzadeh, Jessica L. Huang, et al. · Proceedings of the National Academy of Sciences · 7
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Myosin II tension sensors visualize force generation within the actin cytoskeleton in living cells
2024 · Ryan G. Hart, Divya Kota, et al. · Journal of Cell Science · 11
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Urocortin 3 contributes to paracrine inhibition of islet alpha cells in mice
2024 · Glyn M Noguchi, Vincent C Castillo, et al. · Journal of Endocrinology · 6
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Paracrine signalling by pancreatic δ cells determines the glycaemic set point in mice
2024 · Jessica L. Huang, Mohammad S. Pourhosseinzadeh, et al. · Nature Metabolism · 50
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An Intraislet Paracrine Signaling Pathway That Enables Glucagon to Stimulate Pancreatic β-Cells
2023 · Alejandro Caicedo, Mark O. Huising, et al. · Diabetes · 6
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Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
2023 · Wilma Tixi, Maricela Maldonado, et al. · eLife · 25
Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity
2023 · Jeeyeon Cha, Xin Tong, et al. · JCI Insight · 11
Nutrient regulation of the islet epigenome controls adaptive insulin secretion
2023 · Matthew Wortham, Fenfen Liu, et al. · Journal of Clinical Investigation · 26
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Urocortin3: Local inducer of somatostatin release and bellwether of beta cell maturity
2022 · Marcus F. Flisher, Donghan Shin, et al. · Peptides · 20
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Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering
2021 · Nicole A J Krentz, Lonnie D Shea, et al. · The Lancet Diabetes & Endocrinology · 36
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Temporal coding of ERK signalling in β-cells
2021 · Mark O. Huising, John G. Albeck · Nature Reviews Endocrinology
Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic β-cell dysfunction and loss
2021 · Shinichiro Koike, Ming-Fo Hsu, et al. · Free Radical Biology and Medicine · 7
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Nine residues in HLA-DQ molecules determine with susceptibility and resistance to type 1 diabetes among young children in Sweden
2021 · Lue Ping Zhao, George K. Papadopoulos, et al. · Scientific Reports · 13
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Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice
2021 · Marine L. Croze, Marcus F. Flisher, et al. · Molecular Metabolism · 45
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Paracrine regulation of insulin secretion
2020 · Mark O. Huising · Diabetologia · 112
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Genetic deletion of Urocortin 3 does not prevent functional maturation of beta cells
2020 · Jessica L Huang, Sharon Lee, et al. · Journal of Endocrinology · 18
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Integrating the inputs that shape pancreatic islet hormone release
2019 · Glyn M. Noguchi, Mark O. Huising · Nature Metabolism · 131
Navigating the Depths and Avoiding the Shallows of Pancreatic Islet Cell Transcriptomes
2019 · Alex M. Mawla, Mark O. Huising · Diabetes · 117
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The Difference δ-Cells Make in Glucose Control
2018 · Mark O. Huising, Talitha van der Meulen, et al. · Physiology · 59
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Evidence for a Neogenic Niche at the Periphery of Pancreatic Islets
2018 · Mark O. Huising, Sharon Lee, et al. · BioEssays · 18
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The somatostatin-secreting pancreatic δ-cell in health and disease
2018 · Patrik Rorsman, Mark O. Huising · Nature Reviews Endocrinology · 257
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