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R01 DK099317

Funded outputs count: 58
Funder award ID: R01 DK099317
OpenAlex ID: G7127556104
Beta cell reactivity defines disease-relevant pancreatic CD8 T cells in type 1 diabetes
2026 · Amanda M. Anderson, Laurie G. Landry, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
Autoimmune Type 1 Diabetes in the Era of Disease‐Modifying Immune Therapy
2025 · Aaron W. Michels, Peter A. Gottlieb, et al. · Diabetes/Metabolism Research and Reviews · 5
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Proteogenomic Discovery of Novel Open Reading Frames With HLA Immune Presentation on Human β-Cells
2025 · Kathryn Walters, Roberto Castro-Gutierrez, et al. · Diabetes · 4
Interferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells
2025 · Alexia Carré, Fatoumata Samassa, et al. · Nature Communications · 35
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Strong Association of Autoantibodies Targeting Deamidated Extracellular Epitopes of Insulinoma Antigen-2 With Clinical Onset of Type 1 Diabetes
2025 · Xiaofan Jia, Janet M. Wenzlau, et al. · Diabetes · 2
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Epitope Hierarchy in Type 1 Diabetes Pathogenesis
2024 · Thomas Delong, Maki Nakayama · Cold Spring Harbor Perspectives in Medicine · 2
The Type 1 Diabetes T Cell Receptor and B Cell Receptor Repository in the AIRR Data Commons: a practical guide for access, use and contributions through the Type 1 Diabetes AIRR Consortium
2024 · Stephanie J. Hanna, Rachel H. Bonami, et al. · Diabetologia · 5
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Clinical Features and HLA Genetics Differ in Children at Type 1 Diabetes Onset by Hispanic Ethnicity
2024 · Kagan E Karakus, Theodore Fleury, et al. · The Journal of Clinical Endocrinology & Metabolism · 6
Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas
2024 · Peter S. Linsley, Maki Nakayama, et al. · Nature Communications · 13
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses
2024 · Federica Vecchio, Alexia Carré, et al. · Science Advances · 27
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Routine Blood Glucose Monitoring Does Not Predict Onset of Immune Checkpoint Inhibitor–Induced Type 1 Diabetes
2024 · Halis Kaan Akturk, Kylie Michel, et al. · Diabetes Care · 8
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Tracking DNA-based antigen-specific T cell receptors during progression to type 1 diabetes
2023 · Angela M. Mitchell, Erin E. Baschal, et al. · Science Advances · 22
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HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice
2023 · Jeremy J Racine, Adel Misherghi, et al. · The Journal of Immunology · 11
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Single-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans
2023 · Stephanie J. Hanna, Terri C. Thayer, et al. · Frontiers in Immunology · 16
Stem-Cell-Derived β-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity
2022 · Taylor M. Triolo, J. Quinn Matuschek, et al. · Cells · 7
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Temporal development of T cell receptor repertoires during childhood in health and disease
2022 · Angela M. Mitchell, Erin E. Baschal, et al. · JCI Insight · 25
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Insulin B-chain hybrid peptides are agonists for T cells reactive to insulin B:9-23 in autoimmune diabetes
2022 · Janet M. Wenzlau, James E. DiLisio, et al. · Frontiers in Immunology · 24
Self-Antigens Targeted by Regulatory T Cells in Type 1 Diabetes
2022 · Angela M. Mitchell, Aaron W. Michels · International Journal of Molecular Sciences · 15
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The pathogenesis, natural history, and treatment of type 1 diabetes: time (thankfully) does not stand still
2021 · Aaron W Michels, Maria J Redondo, et al. · The Lancet Diabetes & Endocrinology · 15
Using the T Cell Receptor as a Biomarker in Type 1 Diabetes
2021 · Maki Nakayama, Aaron W. Michels · Frontiers in Immunology · 51
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Human islet T cells are highly reactive to preproinsulin in type 1 diabetes
2021 · Amanda M. Anderson, Laurie G. Landry, et al. · Proceedings of the National Academy of Sciences · 95
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CD8+ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes
2021 · Marie Eliane Azoury, Fatoumata Samassa, et al. · Diabetes · 23
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Characterization of Human CD4 T Cells Specific for a C-Peptide/C-Peptide Hybrid Insulin Peptide
2021 · Timothy A. Wiles, Anita Hohenstein, et al. · Frontiers in Immunology · 33
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Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors
2021 · Laurie G. Landry, Amanda M. Anderson, et al. · Frontiers in Endocrinology · 36
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Beryllium-specific CD4+ T cells induced by chemokine neoantigens perpetuate inflammation
2021 · Michael T. Falta, Jeremy C. Crawford, et al. · Journal of Clinical Investigation · 20
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