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Molecular mechanisms of oxidative stress in aging muscle

Funding type: research
Funder scheme: R01
Start date: 2000-08-01
End date: 2013-06-30
Investigator: CHRISTIAAN LEEUWENBURGH
Institution: UNIVERSITY OF FLORIDA
Funded outputs count: 89
Funder award ID: R01AG017994
OpenAlex ID: G451360555
Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older Adults
2020 · Anna Picca, Sunil K. Saini, et al. · Cells · 31
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Advanced Age Is Associated with Iron Dyshomeostasis and Mitochondrial DNA Damage in Human Skeletal Muscle
2019 · Anna Picca, Robert T. Mankowski, et al. · Cells · 53
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Targeting mitochondrial quality control for treating sarcopenia: lessons from physical exercise
2018 · Anna Picca, Riccardo Calvani, et al. · Expert Opinion on Therapeutic Targets · 42
Administration of Enalapril Started Late in Life Attenuates Hypertrophy and Oxidative Stress Burden, Increases Mitochondrial Mass, and Modulates Mitochondrial Quality Control Signaling in the Rat Heart
2018 · Anna Picca, Giuseppe Sirago, et al. · Biomolecules · 22
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Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart
2018 · Guglielmina Chimienti, Anna Picca, et al. · Free Radical Biology and Medicine · 43
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“What makes some rats live so long?” The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content
2016 · Anna Picca, Vito Pesce, et al. · Experimental Gerontology · 21
Definition as Analytical Strategy in the Study of Religion
2016 · Armin W. Geertz, Jonathan Z. Smith, et al. · 20
A comparison among the tissue-specific effects of aging and calorie restriction on TFAM amount and TFAM-binding activity to mtDNA in rat
2014 · Anna Picca, Vito Pesce, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 44
Aging and Calorie Restriction Oppositely Affect Mitochondrial Biogenesis through TFAM Binding at Both Origins of Mitochondrial DNA Replication in Rat Liver
2013 · Anna Picca, Vito Pesce, et al. · PLoS ONE · 80
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Dysregulation of Mitochondrial Quality Control Processes Contribute to Sarcopenia in a Mouse Model of Premature Aging
2013 · Anna-Maria Joseph, Peter J. Adhihetty, et al. · PLoS ONE · 161
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Short-term caloric restriction, resveratrol, or combined treatment regimens initiated in late-life alter mitochondrial protein expression profiles in a fiber-type specific manner in aged animals
2013 · Anna-Maria Joseph, Angelina G. Malamo, et al. · Experimental Gerontology · 55
Caloric restriction and resveratrol attenuate doxorubicin‐induced vascular dysfunction in old rat mesenteric arteries
2013 · Melissa Ann Whidden, Nataliya Kirichenko, et al. · The FASEB Journal
Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast
2013 · John P. Aris, Ashley L. Alvers, et al. · Experimental Gerontology · 81
Oxidative Damage Increases With Reproductive Energy Expenditure and Is Reduced by Food-supplementation
2012 · Quinn E. Fletcher, Colin Selman, et al. · Evolution · 125
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Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding
2012 · Anna Picca, Flavio Fracasso, et al. · AGE · 62
Impaired Iron Status in Aging Research
2012 · Jinze Xu, Zhenhua Jia, et al. · International Journal of Molecular Sciences · 103
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Critical role of autophagy in ischemia/reperfusion injury to aged livers
2012 · Jin-Hee Wang, Kevin E. Behrns, et al. · Autophagy · 36
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Long-term perturbation of muscle iron homeostasis following hindlimb suspension in old rats is associated with high levels of oxidative stress and impaired recovery from atrophy
2011 · Jinze Xu, Judy C.Y. Hwang, et al. · Experimental Gerontology · 47
Interleukin‐6, C‐Reactive Protein, and Tumor Necrosis Factor‐Alpha as Predictors of Mortality in Frail, Community‐Living Elderly Individuals
2011 · Silvia Giovannini, Graziano Onder, et al. · Journal of the American Geriatrics Society · 249
Autophagy Suppresses Age-Dependent Ischemia and Reperfusion Injury in Livers of Mice
2011 · Jin–Hee Wang, In–Sook Ahn, et al. · Gastroenterology · 146
Amino Acid Homeostasis and Chronological Longevity in Saccharomyces cerevisiae
2011 · John P. Aris, Laura K. Fishwick, et al. · Sub-cellular biochemistry/Subcellular biochemistry · 13
New insights into the role of mitochondria in aging: mitochondrial dynamics and more
2010 · Arnold Y. Seo, Anna-Maria Joseph, et al. · Journal of Cell Science · 522
Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice
2010 · Asimina Hiona, Alberto Sanz, et al. · PLoS ONE · 272
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Calorie Restriction for Optimal Cardiovascular Aging: The Weight of Evidence
2010 · Emanuele Marzetti, Stephanie E. Wohlgemuth, et al. · Current Cardiovascular Risk Reports · 1
Beneficial Effects of a Q-ter® Based Nutritional Mixture on Functional Performance, Mitochondrial Function, and Oxidative Stress in Rats
2010 · Jinze Xu, Arnold Y. Seo, et al. · PLoS ONE · 19
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