Award

JHU-Mayo-NIA Murine Senescence Mapping Program (JMN-MSMP)

Description: The overall goal of the Johns Hopkins-Mayo-NIA Murine Senescence Mapping Program (JMN- MSMP) is to create an Atlas of Senescence in mouse tissues that coincide with tissues being explored in the human SenNet. The JMN-MSMP team combines expertise in aging, senescence, immunology, single-cell analysis, data sciences, and innovative computational approaches to achieve this goal. We will define cellular and molecular features of senescence, elucidate the heterogeneity of senescent cells, and characterize their impact on other cells and tissues.
Funding type: cooperative_agreement
Funder scheme: U54
Start date: 2022-08-01
End date: 2027-07-31
Investigator: DARREN BAKER
Institution: JOHNS HOPKINS UNIVERSITY
Funded outputs count: 38
Funder award ID: U54AG079779
OpenAlex ID: G9000879223
2026 · Joscelyn C. Mejías, Nazmiye Celik, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2026 · Marissa J. Schafer, Nathan Basisty, et al. · Nature Aging · 2
2026 · Sara I. Graves, Pedro Versuti Del Cioppo Vasques, et al. · Neuron
2026 · Jiyeon Song, Alexandra N. Rindone, et al. · Advanced Science · 4
2026 · Rindone, Alexandra, Nagaraj, Sushma, et al. · Zenodo (CERN European Organization for Nuclear Research)
2026 · Vidyani Suryadevara, Negin Farzad, et al. · Cell · 9
2026 · Dmitrijs Lvovs, Jeffrey Quinn, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
2026 · Cristina Correia, Choong Yong Ung, et al. · International Journal of Molecular Sciences
2026 · Coulter Q. Ralston, Andrea Flesken-Nikitin, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2025 · Sara I. Graves, Darren J. Baker · STAR Protocols
2025 · Sheng Li, Paula A. Agudelo Garcia, et al. · Nature Genetics · 40
2025 · Amit K Dey, Bradley Olinger, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
2025 · Bradley Olinger, Reema Banarjee, et al. · Nature Aging · 25
2025 · Dmitrijs Lvovs, Allison L. Creason, et al. · Cell Reports Medicine · 11
2024 · Michael T. Heneka, Wiesje M. van der Flier, et al. · Nature reviews. Immunology · 595
2024 · Mikolaj Ogrodnik, Juan Carlos Acosta, et al. · Cell · 376
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