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R01DK086267
Funder:
National Institute of Diabetes and Digestive and Kidney Diseases
Funded outputs count:
26
Funder award ID:
R01DK086267
OpenAlex ID:
G7190041503
Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization
2022
·
Fiona E. Reed
, Nicole M. Eskow
, et al.
·
Haematologica
·
3
PDF
MRTFA: A critical protein in normal and malignant hematopoiesis and beyond
2021
·
Fiona Reed
, Shannon T. Larsuel
, et al.
·
Journal of Biological Chemistry
·
29
Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice
2019
·
Juliana Xavier-Ferrucio
, Vanessa Scanlon
, et al.
·
Blood
·
82
PDF
Epithelial (E)-Cadherin is a Novel Mediator of Platelet Aggregation and Clot Stability
2019
·
Vanessa Scanlon
, Alexandra Teixeira
, et al.
·
Thrombosis and Haemostasis
·
12
The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate Specification
2018
·
Yi-Chien Lu
, Chad Sanada
, et al.
·
Cell Reports
·
22
PDF
The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate Specification
2018
·
Yi-Chien Lu
, Chad Sanada
, et al.
·
Cell Reports
·
104
PDF
MRTFA augments megakaryocyte maturation by enhancing the SRF regulatory axis
2018
·
Nur-Taz Rahman
, Vincent P. Schulz
, et al.
·
Blood Advances
·
29
Hematopoietic defects in response to reduced Arhgap21
2017
·
Juliana Xavier-Ferrucio
, Lauremília Ricon
, et al.
·
Stem Cell Research
·
22
PDF
SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume
2017
·
Siying Zou
, Alexandra M. Teixeira
, et al.
·
PLoS ONE
·
35
PDF
Adult human megakaryocyte-erythroid progenitors are in the CD34+CD38mid fraction
2016
·
Chad Sanada
, Juliana Xavier-Ferrucio
, et al.
·
Blood
·
79
Leukaemia-associated Rho guanine nucleotide exchange factor (LARG) plays an agonist specific role in platelet function through RhoA activation
2016
·
Siying Zou
, Alexandra M. Teixeira
, et al.
·
Thrombosis and Haemostasis
·
12
Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis
2015
·
Zhenhua Sui
, Roberta B. Nowak
, et al.
·
Blood
·
37
PDF
Stem cell maintenance: aMPLe splicing choices
2015
·
Stephanie Halene
, Diane S. Krause
·
Blood
Nonstochastic Reprogramming from a Privileged Somatic Cell State
2014
·
Shangqin Guo
, Xiaoyuan Zi
, et al.
·
Cell
·
174
PDF
Whole-exome sequencing identifies a novel somatic mutation in MMP8 associated with a t(1;22)-acute megakaryoblastic leukemia
2013
·
Y Kim
, V P Schulz
, et al.
·
Leukemia
·
7
Molecular Pathways: Induction of Polyploidy as a Novel Differentiation Therapy for Leukemia
2013
·
Diane S. Krause
, John D. Crispino
·
Clinical Cancer Research
·
30
Dynamic Migration and Cell-Cell Interactions of Early Reprogramming Revealed by High-Resolution Time-Lapse Imaging
2013
·
Cynthia M. Megyola
, Yuan Gao
, et al.
·
Stem Cells
·
29
PDF
Induction of megakaryocyte differentiation drives nuclear accumulation and transcriptional function of MKL1 via actin polymerization and RhoA activation
2012
·
Elenoe C. Smith
, Alexandra M. Teixeira
, et al.
·
Blood
·
49
MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation
2012
·
Elenoe C. Smith
, Jonathan N. Thon
, et al.
·
Blood
·
62
Role of RhoA-Specific Guanine Exchange Factors in Regulation of Endomitosis in Megakaryocytes
2012
·
Yuan Gao
, Elenoe Smith
, et al.
·
Developmental Cell
·
94
PDF
Serum response factor is an essential transcription factor in megakaryocytic maturation
2010
·
Stephanie Halene
, Yuan Gao
, et al.
·
Blood
·
40
SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis
2010
·
Luyang Yu
, Weidong Ji
, et al.
·
The Journal of Experimental Medicine
·
81
PDF
C/EBPε directs granulocytic-vs-monocytic lineage determination and confers chemotactic function via Hlx
2009
·
Stephanie Halene
, Peter Gaines
, et al.
·
Experimental Hematology
·
31
Fanconi Anemia Complementation Group FANCD2 Protein Serine 331 Phosphorylation Is Important for Fanconi Anemia Pathway Function and BRCA2 Interaction
2009
·
Gang Zhi
, James B. Wilson
, et al.
·
Cancer Research
·
58
Dynamics of α-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34+ cells in culture
2009
·
Milind C. Mahajan
, Subhradip Karmakar
, et al.
·
Experimental Hematology
·
26
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