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25233

Funded outputs count: 69
Funder award ID: 25233
OpenAlex ID: G7228899597
Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control
2025 · Shannon Nicole Russell, Constantinos Demetriou, et al. · Gut · 28
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Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response
2024 · Brooke A. Pereira, Shona Ritchie, et al. · Science Advances · 25
The preclinical gap in pancreatic cancer and radiotherapy
2024 · Mathias Tesson, Jennifer P. Morton · Disease Models & Mechanisms · 6
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Targeted irradiation in an autochthonous mouse model of pancreatic cancer
2024 · Mathias Tesson, Katrina Stevenson, et al. · Disease Models & Mechanisms · 4
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Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis
2024 · Yuliana Astuti, Meirion Raymant, et al. · Nature Cancer · 106
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Tissue-resident natural killer cells support survival in pancreatic cancer through promotion of cDC1-CD8 T activity
2024 · Simei Go, Constantinos Demetriou, et al. · eLife · 8
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Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma
2023 · Vincenzo Graziano, Andreas Dannhorn, et al. · Journal for ImmunoTherapy of Cancer · 30
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USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
2023 · Naiara Perurena, Rebecca Lock, et al. · Cell Reports Medicine · 13
Therapeutic targeting of tumour myeloid cells
2023 · Simon T. Barry, Dmitry I. Gabrilovich, et al. · Nature reviews. Cancer · 305
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Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells
2022 · Christopher J. Halbrook, Galloway Thurston, et al. · Nature Cancer · 80
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Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1
2022 · Abigail S. Coetzee, Edward P. Carter, et al. · Oncogene · 19
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Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging
2022 · Eva C. Freckmann, Emma Sandilands, et al. · Nature Communications · 40
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Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors
2022 · Ali Vaziri-Gohar, Joel Cassel, et al. · Nature Cancer · 86
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LOXL2 in pancreatic tumourigenesis: the complexity of tumour–stromal crosstalk exemplified
2022 · Seth B Coffelt, Jennifer P Morton · Gut · 2
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6
2022 · Andrew M. Kidger, Mark K. Saville, et al. · Oncogene · 38
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Chemotherapy-induced infiltration of neutrophils promotes pancreatic cancer metastasis via Gas6/AXL signalling axis
2022 · Gaia Bellomo, Carolyn Rainer, et al. · Gut · 103
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Heterogeneity in Pancreatic Cancer Fibroblasts—TGFβ as a Master Regulator?
2021 · Dale M. Watt, Jennifer P. Morton · Cancers · 12
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Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status
2021 · Kendelle J. Murphy, Daniel A. Reed, et al. · Science Advances · 51
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A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids
2021 · Christopher R. Below, Joanna Kelly, et al. · Nature Materials · 194
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity
2021 · Colin Hutton, Felix Heider, et al. · Cancer Cell · 337
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Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer
2021 · Chiara Falcomatà, Stefanie Bärthel, et al. · Cancer Discovery · 20
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Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade
2021 · Sebastian R. Nielsen, Jan E. Strøbech, et al. · Nature Communications · 119
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New Insights Into Pancreatic Cancer: Notes from a Virtual Meeting
2021 · Elisabeth Hessmann, Günter Schneider, et al. · Gastroenterology · 5
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Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition
2021 · George Sharbeen, Joshua A. McCarroll, et al. · Cancer Research · 135
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Translating complexity and heterogeneity of pancreatic tumor: 3D in vitro to in vivo models
2021 · Marcel A. Heinrich, Ahmed M.R.H. Mostafa, et al. · Advanced Drug Delivery Reviews · 107
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