Award

Complete regeneration of periodontal tissue by junctional epithellium regeneration

Description: A treatment of periodontal disease purposes to be decreased inflammation and regenerative therapy. Although periodontal regenerative therapy is focused to alveolar bone regeneration, periodontal tissue constitutes not only alveolar bone but also periodontal ligament, gingiva and junctional epithelium. We aspire for perfect regeneration of periodontal tissue. The purpose of this study is to induce iPS cells for periodontal cells, and to evaluate the interaction among various cells in periodontal tissue. This study indicated the conditions for iPS cells to be several kinds of cells in periodontal tissue. Further, some roles of Malassez' epithelial cell for periodontal tissue cells were elucidated.

Funder: Japan Society for the Promotion of Science

Amount: ¥4,680,000

Funding type: research

Funder scheme: Grant-in-Aid for Scientific Research (C)

Start date: 2017-04-01

End date: 2021-03-31

Investigator: Kenichi MATSUZAKA

Institution: Tokyo Dental College

Topic: Periodontal Regeneration and Treatments

Subfield: Urology

Field: Medicine

Domain: Health Sciences