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WT098565/Z/12/Z

Funded outputs count: 20
Funder award ID: WT098565/Z/12/Z
OpenAlex ID: G7248250100
Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity
2023 · Javier Morón-Oset, Lilly Katharina Sophie Fischer, et al. · Acta Neuropathologica Communications · 4
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Toxicity of C9orf72 -associated dipeptide repeat peptides is modified by commonly used protein tags
2023 · Javier Morón-Oset, Lilly KS Fischer, et al. · Life Science Alliance · 7
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Functional conservation in genes and pathways linking ageing and immunity
2021 · Daniel K. Fabian, Matías Fuentealba, et al. · Immunity & Ageing · 73
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Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity
2021 · Teresa Niccoli, Fiona Kerr, et al. · Brain Communications · 12
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Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system
2021 · Ekin Bolukbasi, Nathaniel S. Woodling, et al. · Proceedings of the National Academy of Sciences · 14
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Transposable Element Landscape in Drosophila Populations Selected for Longevity
2021 · Daniel K Fabian, Handan Melike Dönertaş, et al. · Genome Biology and Evolution · 10
From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing
2021 · Maarouf Baghdadi, Helena M Hinterding, et al. · Briefings in Functional Genomics · 9
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Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice
2021 · Matias Fuentealba, Daniel K. Fabian, et al. · Mechanisms of Ageing and Development · 11
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Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling
2020 · Nathaniel S. Woodling, Arjunan Rajasingam, et al. · BMC Biology · 15
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PICALM rescues glutamatergic neurotransmission, behavioural function and survival in a Drosophila model of Aβ42 toxicity
2020 · Yifan Yu, Teresa Niccoli, et al. · Human Molecular Genetics · 16
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Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain
2019 · Javier Morón-Oset, Tessa Supèr, et al. · Acta Neuropathologica Communications · 21
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Longevity in response to lowered insulin signaling requires glycine N‐methyltransferase‐dependent spermidine production
2019 · Luke S. Tain, Chirag Jain, et al. · Aging Cell · 65
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A triple drug combination targeting components of the nutrient-sensing network maximizes longevity
2019 · Jorge Iván Castillo-Quan, Luke S. Tain, et al. · Proceedings of the National Academy of Sciences · 93
Using the drug-protein interactome to identify anti-ageing compounds for humans
2019 · Matías Fuentealba Valenzuela, Handan Melike Dönertaş, et al. · PLoS Computational Biology · 45
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Identifying Potential Ageing-Modulating Drugs In Silico
2018 · Handan Melike Dönertaş, Matías Fuentealba, et al. · Trends in Endocrinology and Metabolism · 27
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A proteomic atlas of insulin signalling reveals tissue‐specific mechanisms of longevity assurance
2017 · Luke S Tain, Robert Sehlke, et al. · Molecular Systems Biology · 46
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Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease
2017 · Fiona Kerr, Oyinkan Sofola-Adesakin, et al. · PLoS Genetics · 146
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Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets
2017 · Adam J. Dobson, Marina Ezcurra, et al. · Cell Reports · 66
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Increased Glucose Transport into Neurons Rescues Aβ Toxicity in Drosophila
2016 · Teresa Niccoli, Melissa Cabecinha, et al. · Current Biology · 112
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Χρήση τεχνικών διαδικτύου για τη λειτουργία των οργάνων της ανώνυμης εταιρείας: νομική-τεχνολογική προσέγγιση.
2013 · Ευστράτιος Μουρατίδης
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