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Insulin Receptors and the Glucose Transport System

Funding type: research
Funder scheme: R37
Start date: 1983-08-01
End date: 2010-06-30
Investigator: JERROLD MICHAEL OLEFSKY
Institution: UNIVERSITY OF CALIFORNIA, SAN DIEGO
Funded outputs count: 69
Funder award ID: R37DK033651
OpenAlex ID: G4452779728
TAZ Is a Negative Regulator of PPARγ Activity in Adipocytes and TAZ Deletion Improves Insulin Sensitivity and Glucose Tolerance
2019 · Dalila El Ouarrat, Roi Isaac, et al. · Cell Metabolism · 103
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Microbiota-Produced N-Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance
2019 · Joshua Wollam, Matthew Riopel, et al. · Diabetes · 35
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Inflammation and insulin resistance: New targets encourage new thinking
2017 · Andrew M. F. Johnson, Shaocong Hou, et al. · BioEssays · 24
Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling
2017 · Wei Ying, Joshua Wollam, et al. · Journal of Clinical Investigation · 128
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Obese neuronal PPARγ knock-out mice are leptin sensitive but show impaired glucose tolerance and fertility
2016 · Marina O. Fernandez, Shweta Sharma, et al. · Endocrinology · 25
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Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance
2016 · Pingping Li, Shuainan Liu, et al. · Cell · 297
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GPR43 Potentiates β-Cell Function in Obesity
2015 · Joanne C. McNelis, Yun Sok Lee, et al. · Diabetes · 224
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Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity
2015 · Rafael Mayoral, Olivia Osborn, et al. · Molecular Metabolism · 169
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LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes
2015 · Pingping Li, Da Young Oh, et al. · Nature Medicine · 315
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
2015 · Sungsoon Fang, Jae Myoung Suh, et al. · Nature Medicine · 737
Characterization of Distinct Subpopulations of Hepatic Macrophages in HFD/Obese Mice
2014 · Hidetaka Morinaga, Rafael Mayoral, et al. · Diabetes · 175
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Knock-Down of IL-1Ra in Obese Mice Decreases Liver Inflammation and Improves Insulin Sensitivity
2014 · Niclas Franck, Michael Maris, et al. · PLoS ONE · 24
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Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer
2014 · Jae Myoung Suh, Johan W. Jonker, et al. · Nature · 258
A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice
2014 · Da Young Oh, Evelyn Walenta, et al. · Nature Medicine · 391
Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity
2014 · Yun Sok Lee, Jung-whan Kim, et al. · Cell · 597
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Quantitative Proteomic and Functional Analysis of Liver Mitochondria from High Fat Diet (HFD) Diabetic Mice
2013 · Yurong Guo, Manjula Darshi, et al. · Molecular & Cellular Proteomics · 77
NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids
2013 · Pingping Li, Nathanael J. Spann, et al. · Cell · 177
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The Fractalkine/CX3CR1 System Regulates β Cell Function and Insulin Secretion
2013 · Yun Sok Lee, Hidetaka Morinaga, et al. · Cell · 141
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Free Fatty Acids Induce Lhb mRNA but Suppress Fshb mRNA in Pituitary LβT2 Gonadotropes and Diet-Induced Obesity Reduces FSH Levels in Male Mice and Disrupts the Proestrous LH/FSH Surge in Female Mice
2013 · Shweta Sharma, Hidetaka Morinaga, et al. · Endocrinology · 40
Neuronal Sirt1 Deficiency Increases Insulin Sensitivity in Both Brain and Peripheral Tissues
2013 · Min Lu, David A. Sarruf, et al. · Journal of Biological Chemistry · 57
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Restoration of Euglycemia After Duodenal Bypass Surgery Is Reliant on Central and Peripheral Inputs in Zucker fa/fa Rats
2012 · Jian Jiao, Eun Ju Bae, et al. · Diabetes · 35
Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3
2012 · Jun Hee Lee, Andrei V. Budanov, et al. · Cell Metabolism · 294
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Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
2012 · Saswata Talukdar, Da Young Oh, et al. · Nature Medicine · 961
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GPR105 Ablation Prevents Inflammation and Improves Insulin Sensitivity in Mice with Diet-Induced Obesity
2012 · Jianfeng Xu, Hidetaka Morinaga, et al. · The Journal of Immunology · 81
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G protein–coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice
2012 · Olivia Osborn, Da Young Oh, et al. · Journal of Clinical Investigation · 67
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