Get started
Award

Center for Aging and Regeneration

Amount: CLP 420,500
Funding type: research
Funder scheme: PIA - APOYO A CENTROS
Start date: 2021-01-01
End date: 2022-12-31
Investigator: NIBALDO INESTROSA CANTIN
Institution: PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Funded outputs count: 14
Funder award ID: ACE210009
OpenAlex ID: G7275951759
PLC-γ-Ca2+ pathway regulates axonal TrkB endocytosis and is required for long-distance propagation of BDNF signaling
2024 · Guillermo Moya-Alvarado, Xavier Valero-Peña, et al. · Frontiers in Molecular Neuroscience · 17
Axonal PLC-γ activity is required for BDNF long-distance signaling
2023 · G Moya-Alvarado, X Valero-Peña, et al. · bioRxiv (Cold Spring Harbor Laboratory)
PDF
Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43A90V mutation display a mild reactive state and release polyP toxic to motoneurons
2023 · Fabiola Rojas, Rodrigo Aguilar, et al. · Frontiers in Cell and Developmental Biology · 14
PDF
BDNF/TrkB signaling endosomes in axons coordinate CREB/mTOR activation and protein synthesis in the cell body to induce dendritic growth in cortical neurons
2023 · Guillermo Moya-Alvarado, Reynaldo Tiburcio-Felix, et al. · eLife · 110
Mild Traumatic Brain Injury Induces Mitochondrial Calcium Overload and Triggers the Upregulation of NCLX in the Hippocampus
2023 · Rodrigo G. Mira, Rodrigo A. Quintanilla, et al. · Antioxidants · 23
PDF
How Many Sirtuin Genes Are Out There? Evolution of Sirtuin Genes in Vertebrates With a Description of a New Family Member
2023 · Juan C Opazo, Michael W Vandewege, et al. · Molecular Biology and Evolution · 19
Inflammation context in Alzheimer’s disease, a relationship intricate to define
2022 · Catalina Novoa, Paulina Salazar, et al. · Biological Research · 200
PDF
Sonic hedgehog is basolaterally sorted from the TGN and transcytosed to the apical domain involving Dispatched-1 at Rab11-ARE
2022 · Lisette Sandoval, Mariana Labarca, et al. · Frontiers in Cell and Developmental Biology · 2
PDF
Menopause and development of Alzheimer’s disease: Roles of neural glucose metabolism and Wnt signaling
2022 · Paulina Villaseca, Pedro Cisternas, et al. · Frontiers in Endocrinology · 19
PDF
Epigenetic Changes and Chromatin Reorganization in Brain Function: Lessons from Fear Memory Ensemble and Alzheimer’s Disease
2022 · Brigitte van Zundert, Martin Montecino · International Journal of Molecular Sciences · 20
PDF
Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism
2022 · Yenniffer Ávalos, María Paz Hernández-Cáceres, et al. · Cell Death and Disease · 39
PDF
The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas
2022 · Luis Antonio Díaz, Eduardo Fuentes-López, et al. · ˜The œLancet. Gastroenterology & hepatology · 70
Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons
2022 · Cristian Arredondo, Carolina Cefaliello, et al. · Neuron · 87
Negative Modulation of Macroautophagy by Stabilized HERPUD1 is Counteracted by an Increased ER-Lysosomal Network With Impact in Drug-Induced Stress Cell Survival
2022 · Gabriela Vargas, Omar Cortés, et al. · Frontiers in Cell and Developmental Biology · 4
Year
Topic