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Targets for selenium in prostate cancer prevention

Funding type: research
Funder scheme: R01
Start date: 2006-08-04
End date: 2011-07-31
Investigator: JOHN T PINTO
Institution: NEW YORK MEDICAL COLLEGE
Funded outputs count: 26
Funder award ID: R01CA111842
OpenAlex ID: G2719685945
Riboflavin
2016 · John T Pinto, Janos Zempleni · Advances in Nutrition · 180
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Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors
2015 · Eunah Kim, William H. Bisson, et al. · Current Topics in Medicinal Chemistry · 80
HDAC8 and STAT3 repress BMF gene activity in colon cancer cells
2014 · Y Kang, H Nian, et al. · Cell Death and Disease · 84
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Kynurenine Aminotransferase III and Glutamine Transaminase L Are Identical Enzymes that have Cysteine S-Conjugate β-Lyase Activity and Can Transaminate l-Selenomethionine
2014 · John T. Pinto, Boris F. Krasnikov, et al. · Journal of Biological Chemistry · 43
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From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of Vitamin D
2014 · John T. Pinto, Arthur J.L. Cooper · Advances in Nutrition · 58
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Methylseleninic acid elevates REDD1 and inhibits prostate cancer cell growth despite AKT activation and mTOR dysregulation in hypoxia
2014 · Indu Sinha, Joshua E. Allen, et al. · Cancer Medicine · 25
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Stable isotope gas chromatography–tandem mass spectrometry determination of aminoethylcysteine ketimine decarboxylated dimer in biological samples
2012 · Dimitrios Tsikas, Christopher E. Evans, et al. · Analytical Biochemistry · 11
Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4‐phenylenebis(methylene)selenocyanate in human prostate cancer cells
2012 · Nicole D. Facompre, Indu Sinha, et al. · International Journal of Cancer · 31
New insights into the metabolism of organomercury compounds: Mercury-containing cysteine S-conjugates are substrates of human glutamine transaminase K and potent inactivators of cystathionine γ-lyase
2011 · Christy C. Bridges, Boris F. Krasnikov, et al. · Archives of Biochemistry and Biophysics · 40
Reversible and irreversible protein glutathionylation: biological and clinical aspects
2011 · Arthur JL Cooper, John T Pinto, et al. · Expert Opinion on Drug Metabolism & Toxicology · 148
Methylseleninic acid downregulates hypoxia‐inducible factor‐1α in invasive prostate cancer
2011 · Indu Sinha, Kevin Null, et al. · International Journal of Cancer · 32
1,4-Phenylenebis(Methylene)Selenocyanate, but Not Selenomethionine, Inhibits Androgen Receptor and Akt Signaling in Human Prostate Cancer Cells
2010 · Nicole D. Facompre, Karam El-Bayoumy, et al. · Cancer Prevention Research · 37
Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds
2010 · John T. Pinto, Jeong-In Lee, et al. · Amino Acids · 61
Cysteine S-conjugate β-lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents
2010 · Arthur J. L. Cooper, Boris F. Krasnikov, et al. · Amino Acids · 104
Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells
2009 · Zoltan Ungvari, Nazar Labinskyy, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 343
Identification of the putative tumor suppressor Nit2 as ω-amidase, an enzyme metabolically linked to glutamine and asparagine transamination
2009 · Boris F. Krasnikov, Chin-Hsiang Chien, et al. · Biochimie · 63
α-Keto Acid Metabolites of Naturally Occurring Organoselenium Compounds as Inhibitors of Histone Deacetylase in Human Prostate Cancer Cells
2009 · Jeong-In Lee, Hui Nian, et al. · Cancer Prevention Research · 92
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1
2009 · Anna Csiszar, Nazar Labinskyy, et al. · Mechanisms of Ageing and Development · 248
-Keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells
2009 · H. Nian, W. H. Bisson, et al. · Carcinogenesis · 78
Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism
2009 · John T. Pinto, Tetyana Khomenko, et al. · Journal of Chromatography B · 41
Assay and purification of ω-amidase/Nit2, a ubiquitously expressed putative tumor suppressor, that catalyzes the deamidation of the α-keto acid analogues of glutamine and asparagine
2009 · Boris F. Krasnikov, Regina Nostramo, et al. · Analytical Biochemistry · 38
Resveratrol induces mitochondrial biogenesis in endothelial cells
2009 · Anna Csiszar, Nazar Labinskyy, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 451
Effects of Naturally Occurring and Synthetic Organoselenium Compounds on Protein Profiling in Androgen Responsive and Androgen Independent Human Prostate Cancer Cells
2008 · Raghu Sinha, John Thomas Pinto, et al. · Nutrition and Cancer · 29
Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate β-lyase
2008 · Arthur J.L. Cooper, John T. Pinto, et al. · Archives of Biochemistry and Biophysics · 50
Differential effects of naturally occurring and synthetic organoselenium compounds on biomarkers in androgen responsive and androgen independent human prostate carcinoma cells
2007 · John T. Pinto, Raghu Sinha, et al. · International Journal of Cancer · 48
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