Award

Recruitment of First-Time, Tenure-Track Faculty Members

Description: Leukemia, Myeloma

Funder: Cancer Prevention and Research Institute of Texas

Amount: $2,000,000

Funding type: grant

Funder scheme: CPRIT Scholar

Start date: 2014-05-21

Investigator: Andre Catic

Institution: Baylor College of Medicine

Funded outputs count: 11

Funder award ID: RR140038

OpenAlex ID: G7358544571

Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing

2024 · Laure Maneix, Polina Iakova, et al. · Nature Cell Biology · 28

Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors

2023 · Xiangdong Lv, Xuan Lu, et al. · Science · 123

Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria

2023 · Sukyeong Lee, Sang Bum Lee, et al. · Nature Communications · 10

Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation

2022 · Laure Maneix, Polina Iakova, et al. · Cancer Research Communications · 8

Imaging-Based Screening of Deubiquitinating Proteases Identifies Otubain-1 as a Stabilizer of c-MYC

2022 · Shannon E. Moree, Laure Maneix, et al. · Cancers · 10

Fructose Causes Liver Damage, Polyploidy, and Dysplasia in the Setting of Short Telomeres and p53 Loss

2021 · Christopher Chronowski, Viktor Akhanov, et al. · Metabolites · 5

The Mitochondrial Protease LonP1 Promotes Proteasome Inhibitor Resistance in Multiple Myeloma

2021 · Laure Maneix, Melanie A. Sweeney, et al. · Cancers · 29

Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions

2020 · Longyong Xu, Xia Liu, et al. · Nature Cell Biology · 58

The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes

2020 · Melanie A. Sweeney, Polina Iakova, et al. · Scientific Reports · 22

Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease

2019 · Hisayuki Amano, Arindam Chaudhury, et al. · Cell Metabolism · 182

Touch and go: nuclear proteolysis in the regulation of metabolic genes and cancer

2016 · Laure Maneix, André Catic · FEBS Letters · 17