Award

Developing a Complex Intervention for the Treatment of Orthostatic Hypotension in Older People

Description: Orthostatic hypotension (OH) occurs when blood pressure drops on standing, but effective treatments are lacking. OBJECTIVES: Develop a non-drug therapy to treat older people with OH. DESIGN: 1. Evaluate existing research and treatments. 2. Determine how non-drug therapies treat OH. 3. Design an appropriate therapy, and clinical trial to evaluate this therapy. OUTCOMES: 1. Summary of existing research. 2. Knowledge about how therapies work. 3. Strategies helping patients adhere to therapies. 4. Protocol to test the resulting therapy. BENEFITS: Short-term: Help 3.5 million older people adhere to existing non-drug therapies. Long-term: improve clinical care of older people with OH.
Amount: £690,300
Funding type: fellowship
Funder scheme: NIHR Fellowships
Start date: 2015-02-01
End date: 2020-01-31
Investigator: James Frith
Institution: The University of Newcastle upon Tyne
Subfield: Surgery
Field: Medicine
Funded outputs count: 29
Funder award ID: CS-2014-14-002
OpenAlex ID: G7372524450
2022 · Jessica Tarn, Evelyn Evans, et al. · Neuromodulation Technology at the Neural Interface · 33
2022 · Manuel Montero-Odasso, Nathalie van der Velde, et al. · Age and Ageing · 1,758
2022 · Jake R Gibbon, Steve W Parry, et al. · Age and Ageing · 12
2022 · Calum A. Hamilton, James Frith, et al. · International Journal of Geriatric Psychiatry · 5
2022 · Calum A. Hamilton, James Frith, et al. · International Journal of Geriatric Psychiatry · 13
2021 · Jake Ryan Gibbon, James Frith · Clinical Autonomic Research · 9
2020 · Jake Ryan Gibbon, James Frith · Drug and Therapeutics Bulletin · 10
2019 · S. Saedah, Nor Izzati Saedon, et al. · Clinical Autonomic Research · 26
2018 · Miles D Witham, Helen C Roberts, et al. · Age and Ageing · 16
2018 · Lisa J. Robinson, Ruth M. Pearce, et al. · BMC Geriatrics · 15
2018 · Nor I’zzati Saedon, Maw Pin Tan, et al. · The Journals of Gerontology Series A · 181
2017 · James Frith · The Annals of Family Medicine · 7
2016 · James Frith, Steve W. Parry · Age and Ageing · 27
2016 · Victoria Strassheim, Julia L. Newton, et al. · Journal of Hypertension · 24
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