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Orbitrap Eclipse Mass Spectrometer for Northwestern University Neuroproteomic Collaboration Hub

Description: PROJECT NARRATIVE The ability to determine changes in protein abundance, turnover, and modifications represent a critical step towards identifying the molecular mechanisms underlying human diseases and disorders. By obtaining this Orbitrap Eclipse mass spectrometer a core group of investigators will be able to address important biomedical questions at an unprecedented level and transform their research programs. Ultimately, this new instrument will provide the necessary analytical power to detect and quantify these changes, elevate our knowledge of disease mechanisms, and significantly accelerate the discovery of drug targets for improving human health.
Amount: $1,347,000
Funding type: grant
Funder scheme: S10
Start date: 2023-03-01
End date: 2024-02-29
Investigator: JEFFREY NICHOLAS SAVAS
Institution: NORTHWESTERN UNIVERSITY
Subfield: Spectroscopy
Field: Chemistry
Funded outputs count: 37
Funder award ID: 1s10od032464-01a1
OpenAlex ID: G7447937091
2026 · Kavitha Mukund, Seth D. Thompson, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2026 · Valentin Duhay, Miaomiao Tian, et al. · Nature Communications · 2
2026 · Nalini R. Rao, Ivan Santiago-Marrero, et al. · Science Translational Medicine · 2
2026 · Xueshui Guo, Ravindra Singh Prajapati, et al. · Nature Communications · 1
2025 · Casey Dalton, Jelena Mojsilovic-Petrovic, et al. · Journal of Neuroscience · 2
2025 · Pia E. Ferle, Niklas Krause, et al. · Proceedings of the National Academy of Sciences · 1
2025 · Cydney M. Martell, Kamil K. Gebis, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3
2025 · Zachary M. Augur, Garrett M. Fogo, et al. · Acta Neuropathologica · 5
2025 · Rafael J. Gonzalez-Ricon, Ashley M. Otero, et al. · Brain Behavior and Immunity · 8
2025 · Srinivas Koutarapu, Junyue Ge, et al. · Nature Communications · 21
2025 · Jean-Michel Paumier, James Zewe, et al. · JCI Insight · 7
2024 · James Coy-Dibley, Nirupa D. Jayaraj, et al. · Neurobiology of Pain · 4
2024 · Andrew C. Fleming, Nalini R. Rao, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2024 · Nalini R. Rao, Olivia DeGulis, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3
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