Award

Methods to Test Lifestyle, Vaginal Microenvironment, and Genitourinary Symptoms across Menopause Transition

Description: Over 50% of postmenopausal women report genitourinary symptoms which result in detriments to their quality of life. Changes in the normal and protective vaginal bacteria (termed vaginal microbiota) accelerate in menopause transition for some women and have been associated with a higher burden of urogenital symptoms; therefore, we aim to determine how vaginal bacterial, metabolite, and immune profiles relate to genitourinary symptoms over time in a large study. The public health impact is to identify molecular targets of intervention which will improve postmenopausal vaginal health and lengthen women's healthspan, a key NIA mission.
Funding type: research
Funder scheme: R56
Start date: 2020-09-30
End date: 2021-08-31
Investigator: REBECCA M. BROTMAN
Institution: UNIVERSITY OF MARYLAND BALTIMORE
Funded outputs count: 9
Funder award ID: R56AG068673
OpenAlex ID: G8593475629
2023 · Rashmita Bajracharya, Jack M. Guralnik, et al. · Journal of the American Geriatrics Society · 3
2022 · Pei-Lun Kuo, Jennifer A. Schrack, et al. · Nature Aging · 92
2022 · Rashmita Bajracharya, Jack M. Guralnik, et al. · Journal of the American Geriatrics Society · 19
2021 · Rodman Turpin, Natalie Slopen, et al. · American Journal of Epidemiology · 29
2021 · Michelle Shardell, Patti E Gravitt, et al. · The Journals of Gerontology Series A · 73
2019 · Marie E Thoma, Rebecca M Brotman, et al. · Sexually Transmitted Infections · 6
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