Mineralocorticoid Antagonism and Endothelial Dysfunction
Description: PUBLIC HEALTH RELEVANCE: The proposed research will determine the effectiveness of blocking aldosterone for improving the health and function of arteries in patients with autosomal dominant polycystic kidney disease (ADPKD). The study also will provide insight into how blocking aldosterone improves artery health by determining the physiological mechanisms (biological reasons) involved. Overall, the proposed research will provide important new scientific evidence upon which physicians can base recommendations to patients with ADPKD to decrease risk of developing cardiovascular diseases.
Funding type: research
Funder scheme: R01
Start date: 2013-06-07
End date: 2017-03-31
Investigator: MICHEL BENJAMIN CHONCHOL
Institution: UNIVERSITY OF COLORADO DENVER
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Funded outputs count: 5
Funder award ID: R01DK097081
OpenAlex ID: G353058980