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Cerebral Small Vessels in Motor and Cognitive Decline: Neuroimaging Signatures of Vulnerability & Resilience

Description: NARRATIVE Difficulty walking and cognitive impairment are common in aging and often associated with changes on brain imaging, but not everyone is afflicted equally. We propose to identify what brain imaging features distinguishes those who age with and without disability. Our findings will inform us about ways to maintain healthy brain aging and prevent dementia and falls.
Funding type: research
Funder scheme: RF1
Start date: 2014-06-01
End date: 2024-03-31
Investigator: FARZANEH A SOROND
Institution: NORTHWESTERN UNIVERSITY AT CHICAGO
Funded outputs count: 30
Funder award ID: RF1NS085002
OpenAlex ID: G3653434107
2026 · Shahin Yaghoobi, Fatemeh Salboukh, et al. · Stroke
2024 · Matthew B. Maas, Simin Mahinrad, et al. · Hypertension · 7
2024 · Amy E Krefman, John Stephen, et al. · International Journal of Epidemiology · 5
2023 · Milagros C. Romay, Russell H. Knutsen, et al. · Journal of Clinical Investigation · 59
2023 · Philip B. Gorelick, Farzaneh A. Sorond · Cerebral Circulation - Cognition and Behavior · 24
2023 · Philip B Gorelick, Farzaneh A Sorond · The Lancet Neurology · 9
2023 · Behnam Sabayan, Sara Doyle, et al. · The Lancet Healthy Longevity · 47
2023 · Simin Mahinrad, David A. Bennett, et al. · Alzheimer s & Dementia · 32
2022 · Christina M. Lineback, Brian Stamm, et al. · GeroScience · 19
2022 · Felicia C. Chow, Fang Zhao, et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes · 1
2022 · Sanaz Sedaghat, Pamela L. Lutsey, et al. · Alzheimer s & Dementia · 18
2022 · Simin Mahinrad, Farzaneh Sorond, et al. · Clinics in Geriatric Medicine · 23
2022 · Selen C. Muratoglu, Marc F. Charette, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 9
2022 · Simin Mahinrad, Can Ozan Tan, et al. · Journal of Magnetic Resonance Imaging · 8
2022 · Philip B Gorelick, Farzaneh Sorond · The Lancet Healthy Longevity
2021 · Zoltan Ungvari, Peter Toth, et al. · Nature Reviews Nephrology · 545
2016 · Achille E. Tchalla, Gregory A. Wellenius, et al. · The Journals of Gerontology Series A · 44
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