Study of the relationship between oral function and cognitive decline in elderly people
Description: Mild cognitive impairment (MCI) is known as the preliminary phase of dementia. Patients with this condition are at a risk of developing dementia; however, they might also revert to normal. The aim of this study was to examine whether the management of oral functions in the dental clinic can prevent cognitive decline in the elderly.The total number of participants in this study was 52, and data was collected from 35 participants after 2 years. They got a dental check-up regularly and received dental treatment as needed. For the assessment of cognitive decline, the MoCA-J, MMSE and MCI biomarker levels in the blood were used. Oral function was evaluated by tongue pressure and masticatory performance.One out of 23 participants had MCI, and 8 out of 12 MCI participants reverted to normal conditions. Improvement in tongue pressure was associated with the MMSE score. Furthermore, improvement in the masticatory performance was associated with the MMSE score and MCI biomarker levels.
Amount: ¥4,030,000
Funding type: fellowship
Funder scheme: Grant-in-Aid for Young Scientists (B)
Start date: 2017-04-01
End date: 2020-03-31
Investigator: Shinsuke Mizutani
Institution: Kyushu University(2018-2019)Fukuoka Dental College(2017)
Funded outputs count: 4
Funder award ID: 17K17390
OpenAlex ID: G7621119927