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R01-DK-077096

Funded outputs count: 28
Funder award ID: R01-DK-077096
OpenAlex ID: G764387803
The many lives of Myc in the pancreatic β-cell
2020 · Carolina Rosselot, Sharon Baumel-Alterzon, et al. · Journal of Biological Chemistry · 27
Nrf2: The Master and Captain of Beta Cell Fate
2020 · Sharon Baumel-Alterzon, Liora S. Katz, et al. · Trends in Endocrinology and Metabolism · 105
Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis
2019 · Esther M. Levasseur, Kentaro Yamada, et al. · Science Signaling · 58
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Myc Is Required for Adaptive β-Cell Replication in Young Mice but Is Not Sufficient in One-Year-Old Mice Fed With a High-Fat Diet
2019 · Carolina Rosselot, Anil Kumar, et al. · Diabetes · 36
PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2
2016 · Jayalakshmi Lakshmipathi, Juan Carlos Alvarez-Perez, et al. · Diabetes · 47
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Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor
2016 · Rachel E. Stamateris, Rohit B. Sharma, et al. · Diabetes · 99
Human β-Cell Proliferation and Intracellular Signaling: Part 3
2015 · Andrew F. Stewart, Mehboob A. Hussain, et al. · Diabetes · 142
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A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication
2015 · Peng Wang, Juan-Carlos Alvarez-Perez, et al. · Nature Medicine · 404
Diabetes mellitus—advances and challenges in human β-cell proliferation
2015 · Peng Wang, Nathalie M. Fiaschi-Taesch, et al. · Nature Reviews Endocrinology · 205
Phospho-BAD BH3 Mimicry Protects β Cells and Restores Functional β Cell Mass in Diabetes
2015 · Sanda Ljubicic, Klaudia Polak, et al. · Cell Reports · 35
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Hepatocyte Growth Factor Ameliorates Hyperglycemia and Corrects β-Cell Mass in IRS2-Deficient Mice
2014 · Juan C. Alvarez-Perez, Taylor C. Rosa, et al. · Molecular Endocrinology · 13
“RAS”ling β cells to proliferate for diabetes: why do we need MEN?
2014 · Adolfo García-Ocaña, Andrew F. Stewart · Journal of Clinical Investigation · 9
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Human β-Cell Proliferation and Intracellular Signaling Part 2: Still Driving in the Dark Without a Road Map
2014 · Ernesto Bernal-Mizrachi, Rohit N. Kulkarni, et al. · Diabetes · 171
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Hepatocyte Growth Factor/c-Met Signaling Is Required for β-Cell Regeneration
2013 · Juan Carlos Alvarez-Perez, Sara Ernst, et al. · Diabetes · 70
Human β-Cell Proliferation and Intracellular Signaling
2012 · Rohit N. Kulkarni, Ernesto-Bernal Mizrachi, et al. · Diabetes · 236
ChREBP Mediates Glucose-Stimulated Pancreatic β-Cell Proliferation
2012 · Mallikarjuna R. Metukuri, Pili Zhang, et al. · Diabetes · 106
Loss of HGF/c-Met Signaling in Pancreatic β-Cells Leads to Incomplete Maternal β-Cell Adaptation and Gestational Diabetes Mellitus
2012 · Cem Demirci, Sara Ernst, et al. · Diabetes · 116
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Simultaneous Measurement of Insulin Sensitivity, Insulin Secretion, and the Disposition Index in Conscious Unhandled Mice
2012 · Laura C. Alonso, Yoshio Watanabe, et al. · Obesity · 46
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Free Fatty Acids Block Glucose-Induced β-Cell Proliferation in Mice by Inducing Cell Cycle Inhibitors p16 and p18
2012 · Jordan Pascoe, Douglas Hollern, et al. · Diabetes · 74
Activation of Protein Kinase C-ζ in Pancreatic β-Cells In Vivo Improves Glucose Tolerance and Induces β-Cell Expansion via mTOR Activation
2011 · Silvia Velazquez-Garcia, Shelley Valle, et al. · Diabetes · 44
Systemic and acute administration of parathyroid hormone-related peptide(1–36) stimulates endogenous beta cell proliferation while preserving function in adult mice
2011 · K. Williams, D. Abanquah, et al. · Diabetologia · 30
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Disruption of Hepatocyte Growth Factor/c-Met Signaling Enhances Pancreatic β-Cell Death and Accelerates the Onset of Diabetes
2010 · Jose Mellado-Gil, Taylor C. Rosa, et al. · Diabetes · 113
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Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD–severe combined immunodeficiency (SCID) mice
2010 · H. E. Levitt, T. J. Cyphert, et al. · Diabetologia · 109
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Parathyroid Hormone–Related Protein Enhances Human β-Cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression
2010 · Nagesha Guthalu Kondegowda, Sheela Joshi-Gokhale, et al. · Diabetes · 67
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Novel Proapoptotic Effect of Hepatocyte Growth Factor: Synergy with Palmitate to Cause Pancreatic β-Cell Apoptosis
2010 · José A. González-Pertusa, John Dubé, et al. · Endocrinology · 16
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