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82372604

Funded outputs count: 15
Funder award ID: 82372604
OpenAlex ID: G7676792117
NSD2 deficiency disrupts the epigenetic landscape of cochlear hair cells to enhance ECM expression and to perturb cochlear hair cell function
2026 · Ziyi Wang, Yue Xu, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Intestinal epithelial SETD2 maintains gut microbial homeostasis to attenuate colitis
2026 · Jing Feng, Ziyi Wang, et al. · Clinical and Translational Medicine
NSD2 inhibits the expression of PD-L1 via oxidative phosphorylation to control immune surveillance in hepatocellular carcinoma
2026 · Wei Zhang, Wenxin Feng, et al. · Cell Death and Disease
Histone 3 lysine 36 trimethylation by SETD2 shapes an epigenetic landscape in intestinal stem cells to orchestrate lipid metabolism and attenuate cell senescence
2026 · Yue Xu, Ziyi Wang, et al. · Cell Death and Disease · 1
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Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
2026 · Hanyu Rao, Aiting Wang, et al. · Advanced Science · 2
SETD2 orchestrates cholesterol biosynthesis to regulate macrophage polarization and attenuate colitis-associated colorectal cancer
2026 · Wei Zhang, Ziyi Wang, et al. · SSRN Electronic Journal
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NSD2 promotes cell durotaxis and drives the transition from polycystic kidney disease to tubulocystic renal cell carcinoma through integrin/FAK/AKT signaling
2025 · Wenxin Feng, Ningyuan Liu, et al. · Oncogene · 2
Histone 3 lysine 36 trimethylation by SETD2 shapes an epigenetic landscape in intestinal stem cells to orchestrate lipid metabolism and prevent cell senescence
2025 · Yue Xu, Ziyi Wang, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Targeted delivery of Grem1 and IL-10 separately by mesenchymal stem cells effectively mitigates SETD2-deficient inflammatory bowel disease
2025 · Rebiguli Aji, Yue Xu, et al. · Theranostics · 7
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Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption
2024 · Yue Xu, Xiuying Xiao, et al. · Clinical and Translational Medicine · 4
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Multilevel Regulation of NF‐κB Signaling by NSD2 Suppresses Kras‐Driven Pancreatic Tumorigenesis
2024 · Wenxin Feng, Ningning Niu, et al. · Advanced Science · 7
SETD2 deficiency accelerates sphingomyelin accumulation and promotes the development of renal cancer
2023 · Hanyu Rao, Changwei Liu, et al. · Nature Communications · 36
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SETD2 deficiency promotes renal fibrosis through the TGF‐β/Smad signalling pathway in the absence of VHL
2023 · Changwei Liu, Li Ni, et al. · Clinical and Translational Medicine · 7
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Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway
2023 · Chunxiao Ma, Min Liu, et al. · Clinical and Translational Medicine · 14
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Setd2 deficiency promotes gastric tumorigenesis through inhibiting the SIRT1/FOXO pathway
2023 · Wenxin Feng, Chunxiao Ma, et al. · Cancer Letters · 21
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