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The association between urinary female hormone and isoflavone levels and estrogen-dependent gynecological diseases

Description: Equol is one of the soy isoflavones and expected to be beneficial to women’s health, but there were no robust equol cutoff criterion for equol producer classification. So, we defined participants with log10-transformed equol/daidzein ratios ≧ －1.42 in urinary concentration as equol producers.We also reported that the lifetime prevalence of exogenous hormone use in Japanese nurses were 6.0% for oral contraceptives and 13.8% for hormone replacement therapy. Furthermore, we validated the self-reported osteoporosis and gynaecological and breast cancers in the Japan Nurses’ Health Study.

Funder: Japan Society for the Promotion of Science

Amount: ¥4,810,000

Funding type: research

Funder scheme: Grant-in-Aid for Scientific Research (C)

Start date: 2016-04-01

End date: 2021-03-31

Investigator: Yuki Ideno

Institution: Gunma University

Topic: Phytoestrogen effects and research

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences