Identifying Vitamin K Dependent Pathways in Osteoarthritis Progression
Description: PUBLIC HEALTH RELEVANCE: Osteoarthritis is the leading cause of lower-extremity disability, afflicting nearly 27 million Americans, and there is currently no proven therapy to delay its progression. Low vitamin K status has been associated with more severe osteoarthritis population-based studies. While vitamin K dependent processes are implicated in joint function, mechanisms of how vitamin K affects OA have not been well-studied. A better understanding of how vitamins K influences osteoarthritis progression is important because nutrient intakes are modifiable and may represent a novel and achievable approach by which to reduce disease progression.
Funding type: career_development
Funder scheme: K01
Start date: 2012-08-01
End date: 2018-07-31
Investigator: MARY KYLA SHEA
Institution: TUFTS UNIVERSITY BOSTON
Topic: Vitamin K Research Studies
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Funded outputs count: 12
Funder award ID: K01AR063167
OpenAlex ID: G5166609580