Award

R01 DK061153

Funder: National Institute of Diabetes and Digestive and Kidney Diseases

Funded outputs count: 14

Funder award ID: R01 DK061153

OpenAlex ID: G7875712412

p27T187A knockin identifies Skp2/Cks1 pocket inhibitors for advanced prostate cancer

2016 · H Zhao, Z Lu, et al. · Oncogene · 26

Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis

2016 · Hongling Zhao, Hongbo Wang, et al. · Journal of Biological Chemistry · 11

Substituting Threonine 187 with Alanine in p27Kip1 Prevents Pituitary Tumorigenesis by Two-Hit Loss of Rb1 and Enhances Humoral Immunity in Old Age

2015 · Hongling Zhao, Frederick Bauzon, et al. · Journal of Biological Chemistry · 12

Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity

2014 · Zhonglei Lu, Frederick Bauzon, et al. · Nature Communications · 51

Skp2 Deletion Unmasks a p27 Safeguard that Blocks Tumorigenesis in the Absence of pRb and p53 Tumor Suppressors

2013 · Hongling Zhao, Frederick Bauzon, et al. · Cancer Cell · 82

pRb is an obesity suppressor in hypothalamus and high‐fat diet inhibits pRb in this location

2013 · Zhonglei Lu, Genevieve Marcelin, et al. · The EMBO Journal · 24

MicroRNA‐23b cluster microRNAs regulate transforming growth factor‐beta/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads†

2009 · Charles E. Rogler, Lauretta LeVoci, et al. · Hepatology · 208

Elevated Expression of the miR-17–92 Polycistron and miR-21 in Hepadnavirus-Associated Hepatocellular Carcinoma Contributes to the Malignant Phenotype

2008 · Erin Connolly, Margherita Melegari, et al. · American Journal Of Pathology · 248

Clonal, cultured, murine fetal liver hepatoblasts maintain liver specification in chimeric mice

2007 · Charles E. Rogler, Hong Chou Zhou, et al. · Hepatology · 6

New cell surface markers for murine fetal hepatic stem cells identified through high density complementary DNA microarrays†

2007 · Dirk Nierhoff, Lauretta Levoci, et al. · Hepatology · 45

Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liver

2007 · Hongchao Zhou, Leslie E. Rogler, et al. · Hepatology · 144

Transcriptional profiling implicates TGFβ/BMP and Notch signaling pathways in ductular differentiation of fetal murine hepatoblasts

2006 · Tammy Ader, Raquel Norel, et al. · Mechanisms of Development · 63

cDNA microarray analysis of HBV transgenic mouse liver identifies genes in lipid biosynthetic and growth control pathways affected by HBV

2005 · Mustapha Hajjou, Raquel Norel, et al. · Journal of Medical Virology · 80

Genomic expression analysis implicates Wnt signaling pathway and extracellular matrix alterations in hepatic specification and differentiation of murine hepatic stem cells

2001 · Christopher P. Plescia, Charles E. Rogler, et al. · Differentiation · 45