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28647
Funder:
Cancer Research UK
Funded outputs count:
25
Funder award ID:
28647
OpenAlex ID:
G7907355084
Detection of senescence using machine learning algorithms based on nuclear features
2024
·
Imanol Duran
, Joaquim Pombo
, et al.
·
Nature Communications
·
85
PDF
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells
2023
·
Domhnall McHugh
, Bin Sun
, et al.
·
Nature Cell Biology
·
60
PDF
The challenge of identifying senescent cells
2023
·
Jesús Gil
·
Nature Cell Biology
·
58
Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance
2023
·
Christina Guo
, Adam Sharp
, et al.
·
Nature
·
143
PDF
Proteome-wide structural analysis identifies warhead- and coverage-specific biases in cysteine-focused chemoproteomics
2023
·
Matthew E.H. White
, Jesús Gil
, et al.
·
Cell chemical biology
·
48
PDF
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer
2023
·
Scott Haston
, Estela Gonzalez-Gualda
, et al.
·
Cancer Cell
·
251
PDF
Reshaping of the tumor microenvironment by cellular senescence: An opportunity for senotherapies
2023
·
Mariantonietta D’Ambrosio
, Jesús Gil
·
Developmental Cell
·
109
Spurious transcription may be a hallmark of aging
2023
·
Nikita Isima
, Jesús Gil
·
Nature Aging
·
2
3-Deazaadenosine alleviates senescence to promote cellular fitness and cell therapy efficiency in mice
2022
·
Ana Guerrero
, Andrew J. Innes
, et al.
·
Nature Aging
·
16
PDF
Targeting senescence as an anticancer therapy
2022
·
Laura Bousset
, Jesús Gil
·
Molecular Oncology
·
107
PDF
Clearing stressed cells
2021
·
Virinder Reen
, Jesús Gil
·
Science
·
1
Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy
2021
·
Pataje G Prasanna
, Deborah E Citrin
, et al.
·
JNCI Journal of the National Cancer Institute
·
353
PDF
XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence
2021
·
Andrew J. Innes
, Bin Sun
, et al.
·
Genes & Development
·
30
PDF
High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging
2021
·
Junyu Chen
, Unnikrishnan Sivan
, et al.
·
Science Advances
·
112
Similarities and interplay between senescent cells and macrophages
2020
·
Jacques Behmoaras
, Jesús Gil
·
The Journal of Cell Biology
·
158
PDF
Senescence and the SASP: many therapeutic avenues
2020
·
Jodie Birch
, Jesús Gil
·
Genes & Development
·
1,176
PDF
Advanced Prostate Cancer with ATM Loss: PARP and ATR Inhibitors
2020
·
Antje Neeb
, Nicolás Herranz
, et al.
·
European Urology
·
124
T cells engineered to target senescence
2020
·
Verena Wagner
, Jesús Gil
·
Nature
·
9
Prostate carcinogenesis: inflammatory storms
2020
·
Johann S. de Bono
, Christina Guo
, et al.
·
Nature reviews. Cancer
·
230
Senescence as a therapeutically relevant response to CDK4/6 inhibitors
2020
·
Verena Wagner
, Jesús Gil
·
Oncogene
·
148
AP-1 imprints a reversible transcriptional programme of senescent cells
2020
·
Ricardo Iván Martínez-Zamudio
, Pierre-François Roux
, et al.
·
Nature Cell Biology
·
236
Galactose‐modified duocarmycin prodrugs as senolytics
2020
·
Ana Guerrero
, Romain Guiho
, et al.
·
Aging Cell
·
172
PDF
Cardiac glycosides are broad-spectrum senolytics
2019
·
Ana Guerrero
, Nicolás Herranz
, et al.
·
Nature Metabolism
·
359
Cellular Senescence: Defining a Path Forward
2019
·
Vassilis Gorgoulis
, Peter D. Adams
, et al.
·
Cell
·
3,223
PDF
IMR90 ER:RAS: A Cell Model of Oncogene-Induced Senescence
2018
·
Andrew J. Innes
, Jesús Gil
·
Methods in molecular biology
·
25
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