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211002
Funder:
National Institutes of Health
Funded outputs count:
177
Funder award ID:
211002
OpenAlex ID:
G7924111682
APOE4 Drives Uniquely Dysfunctional Human Microglial States in Alzheimer’s Disease
2026
·
Rachel Ee
, Meelad Amouzgar
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Pathology and Genetics in a Global Cohort of Parkinsonian Disorders
2026
·
Lesley Y. Wu
, Tessa du Toit
, et al.
·
JAMA Neurology
·
4
PDF
Mapping cross‐domain drivers of Alzheimer's disease risk through integrated network analysis
2026
·
Gregory A Cary
, Stephen Keegan
, et al.
·
Alzheimer s & Dementia
·
1
Brain-Only Versus GI-Only Synucleinopathy: A Comprehensive Autopsy Study With Both IHC and SAA
2026
·
Christina D. Orru
, Thomas G. Beach
, et al.
·
medRxiv
·
2
PDF
The Genetics of TDP-43 Type C Neurodegeneration
2026
·
Malik Nassan
, Ivan Ayala
, et al.
·
Neurology Genetics
TAS2R38 taster variants-linked MGAM expression in Alzheimer’s disease: a novel target for precision drug repurposing
2026
·
Claire W. Su
, Kewei Chen
, et al.
·
Frontiers in Aging Neuroscience
PDF
Parkinson’s disease-associated alterations in DNA methylation and hydroxymethylation in human brain
2025
·
Juliana I. Choza
, Mahek Virani
, et al.
·
npj Parkinson s Disease
·
8
PDF
Assessment of [125I]a-Bungarotoxin Binding to a7 Nicotinic Acetylcholinergic Receptors in Hippocampus-Subiculum of Postmortem Human Parkinson’s Disease Brain
2025
·
Fariha Karim
, Allyson Ngo
, et al.
·
Biomolecules
·
1
PDF
Integrated phenotypic and proteomic screening identifies top‐tier Alzheimer's disease therapeutic targets
2025
·
Gregory A. Cary
, Qianjin Li
, et al.
·
Alzheimer s & Dementia
·
4
PDF
Transcriptomic profiling of the middle temporal gyrus reveals differential glial/neuronal dysregulation across Alzheimer’s disease and aging
2025
·
IS Piras
, A Bonfitto
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
2
PDF
Lysosomal proteomics reveals mechanisms of neuronal APOE4-associated lysosomal dysfunction
2025
·
Einar K. Krogsaeter
, Justin McKetney
, et al.
·
Autophagy
·
20
Long-Read epigenetic clocks identify improved brain aging predictions
2025
·
Spencer M. Grant
, Sarah J. Eger
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex
2025
·
Rik Ossenkoppele
, Emma M. Coomans
, et al.
·
Nature Neuroscience
·
56
PDF
Insights into ancestral diversity in Parkinson’s disease risk: a comparative assessment of polygenic risk scores
2025
·
Paula Saffie-Awad
, Spencer M. Grant
, et al.
·
npj Parkinson s Disease
·
6
PDF
[125I]IPPI for Tau Imaging: Binding Studies in Postmortem Human Alzheimer's Disease Hippocampus‐Subiculum and Evaluation of Drug Effects
2025
·
Fariha Karim
, Brooke A. Delaney
, et al.
·
Synapse
·
6
PDF
Analysis of the splicing landscape of the frontal cortex in FTLD-TDP reveals subtype specific patterns and cryptic splicing
2025
·
Júlia Faura
, Bavo Heeman
, et al.
·
Acta Neuropathologica
·
8
PDF
Effective integration of multi-omics with prior knowledge to identify biomarkers via explainable graph neural networks
2025
·
Rohit K. Tripathy
, Zachary Frohock
, et al.
·
npj Systems Biology and Applications
·
36
PDF
Alzheimer's Disease Sequencing Project release 4 whole genome sequencing dataset
2025
·
Yuk Yee Leung
, Wan‐Ping Lee
, et al.
·
Alzheimer s & Dementia
·
36
PDF
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau
2025
·
Diana Acosta Ingram
, Emir Turkes
, et al.
·
Nature Communications
·
11
PDF
Distinct neuronal vulnerability and metabolic dysfunctions are characteristic features of fast-progressing Alzheimer's patients with Lewy bodies
2025
·
Mohammed Waseequr Rahman
, Preeti Sharma
, et al.
·
Journal of Biological Chemistry
·
2
PDF
Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells
2025
·
Hui Wang
, Timothy S. Chang
, et al.
·
Movement Disorders
·
7
14-3-3θ phosphorylation exacerbates alpha-synuclein aggregation and toxicity
2025
·
Bing Wang
, Mary Gannon
, et al.
·
Neurobiology of Disease
·
5
Cerebellum mitochondrial DNA copy number is increased in Parkinson’s disease
2025
·
Talia Beglarian
, David R Tyrpak
, et al.
·
Brain Communications
·
3
PDF
Alzheimer's disease‐associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain
2024
·
Benjamin P. Readhead
, Diego F. Mastroeni
, et al.
·
Alzheimer s & Dementia
·
19
PDF
Comparative brain metabolomics reveals shared and distinct metabolic alterations in Alzheimer's disease and progressive supranuclear palsy
2024
·
Richa Batra
, Jan Krumsiek
, et al.
·
Alzheimer s & Dementia
·
33
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