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MC_G1000734

Funded outputs count: 210
Funder award ID: MC_G1000734
OpenAlex ID: G7926448277
Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death
2020 · Craig Hughes, Minee L. Choi, et al. · Communications Biology · 107
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Metabolic response to Parkinson's disease recapitulated by the haploinsufficient diploid yeast cells hemizygous for the adrenodoxin reductase gene
2019 · Duygu Dikicioglu, James W. M T Coxon, et al. · Molecular Omics
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Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans
2019 · Chaolie Huang, Sara Wagner-Valladolid, et al. · eLife · 79
Structural progression of amyloid-β Arctic mutant aggregation in cells revealed by multiparametric imaging
2018 · Meng Lu, Neil Williamson, et al. · Journal of Biological Chemistry · 39
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Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
2018 · Vivek Swarup, Flora I. Hinz, et al. · Nature Medicine · 136
Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution
2018 · Christopher G. Taylor, Georg Meisl, et al. · Analytical Chemistry · 29
Different Structural Conformers of Monomeric α-Synuclein Identified after Lyophilizing and Freezing
2018 · Amberley D. Stephens, Nadezhda Nespovitaya, et al. · Analytical Chemistry · 34
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Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study
2017 · Rita Guerreiro, Owen A Ross, et al. · The Lancet Neurology · 278
Inhibiting the Ca2+ Influx Induced by Human CSF
2017 · Anna Drews, Suman De, et al. · Cell Reports · 32
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TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant
2017 · Peter Thornton, Jean Sevalle, et al. · EMBO Molecular Medicine · 200
Ultra-rare mutations in SRCAP segregate in Caribbean Hispanic families with Alzheimer disease
2017 · Badri N. Vardarajan, Giuseppe Tosto, et al. · Neurology Genetics · 11
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Dendritic spine anomalies and PTEN alterations in a mouse model of VPA-induced autism spectrum disorder
2017 · Usman Mahmood, Sangzin Ahn, et al. · Pharmacological Research · 51
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
2017 · Rebecca Sims, GERAD/PERADES, CHARGE, ADGC, EADI, et al. · Nature Genetics · 1,009
Deciphering microglial diversity in Alzheimer's disease
2017 · Guy C. Brown, Peter H. St George-Hyslop · Science · 17
Correlative STED and Atomic Force Microscopy on Live Astrocytes Reveals Plasticity of Cytoskeletal Structure and Membrane Physical Properties during Polarized Migration
2017 · Nathan Curry, Grégory Ghézali, et al. · Frontiers in Cellular Neuroscience · 58
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Glucocorticoids activate a synapse weakening pathway culminating in tau phosphorylation in the hippocampus
2017 · Jee Hyun Yi, Christopher Brown, et al. · Pharmacological Research · 36
Structural and Chemical Biology of Presenilin Complexes
2017 · Douglas S. Johnson, Yue-Ming Li, et al. · Cold Spring Harbor Perspectives in Medicine · 18
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Heparin acts as a structural component of β-endorphin amyloid fibrils rather than a simple aggregation promoter
2016 · N. Nespovitaya, P. Mahou, et al. · Chemical Communications · 14
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Huntington’s Disease: Mechanisms of Pathogenesis and Therapeutic Strategies
2016 · Maria Jimenez-Sanchez, Floriana Licitra, et al. · Cold Spring Harbor Perspectives in Medicine · 509
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CCT complex restricts neuropathogenic protein aggregation via autophagy
2016 · Mariana Pavel, Sara Imarisio, et al. · Nature Communications · 140
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Fluorescence Self-Quenching from Reporter Dyes Informs on the Structural Properties of Amyloid Clusters Formed in Vitro and in Cells
2016 · WeiYue Chen, Laurence J. Young, et al. · Nano Letters · 80
De novo design of a biologically active amyloid
2016 · Rodrigo Gallardo, Meine Ramakers, et al. · Science · 72
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Structural basis of synaptic vesicle assembly promoted by α-synuclein
2016 · Giuliana Fusco, Tillmann Pape, et al. · Nature Communications · 255
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Probing amyloid protein aggregation with optical superresolution methods: from the test tube to models of disease
2016 · Clemens F. Kaminski, Gabriele S. Kaminski Schierle · Neurophotonics · 42
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From single-molecule spectroscopy to super-resolution imaging of the neuron: a review
2016 · Romain F Laine, Gabriele S Kaminski Schierle, et al. · Methods and Applications in Fluorescence · 27
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