The Impact of Obesity on Radiotherapy Anti-Tumor Effects
Description: Narrative Obesity will soon be the leading cause of preventable cancers and a large proportion of cancer patients are obese, but little is understood about how obesity influences the effectiveness of cancer therapy. Clinical studies as well as our pre-clinical data show that obese cancer patients are more resistant to radiotherapy and have higher rates of cancer recurrence. Based on our previous data showing that obesity profoundly impacts tumor biology we will examine mechanisms inducing radiotherapy resistance and how to improve outcomes in obese patients.
Funder: National Cancer Institute
Funding type: research
Funder scheme: R01
Start date: 2022-03-01
End date: 2027-02-28
Investigator: ARTA MONIR MONJAZEB
Institution: UNIVERSITY OF CALIFORNIA AT DAVIS
Funded outputs count: 10
Funder award ID: R01CA240751
OpenAlex ID: G9000888541