Improvement of Autobiographical Memory In Mild Cognitive Impairment using transcranial alternating current stimulation (tACS) guided by high-density EEG and MRI
Description: <p>I will combine scientific, technological, and clinical approaches to assess the role of brain oscillations in autobiographical memory. First, I will evaluate brain activity during ABM tasks using high-density electroencephalography in cognitively-unimpaired older adults and age-matched patients with Mild Cognitive Impairment (MCI). I will then employ personalized, multi-channel transcranial alternating current stimulation (tACS) to modulate brain oscillations and evaluate the impact on ABM. Finally, I aim to establish a critically needed, therapeutic, long-term, and remotely supervised home-based tACS treatment for memory dysfunction in MCI patients.</p><p>This translational project will make contributions relevant to clinical application and individualized therapy for dementia and age-related memory deficits. Specifically, we will learn about the possibility of reducing memory deficits in MCI patients. </p><br>
Amount: CHF 904,500
Funding type: fellowship
Funder scheme: Ambizione
Start date: 2023-03-01
End date: 2027-02-28
Investigator: Bréchet, Lucie
Institution: University of Geneva – GE
Funded outputs count: 7
Funder award ID: 208686
OpenAlex ID: G7940409560