Clarification of cancer progression mechanism based on the movement of tumor cells infiltration
Description: Although it has long been recognized that the characteristics of tumor cell dynamics are extremely important factors in the progression of malignant tumors, it has been difficult to obtain information on cell dynamics from conventional tissue specimens. In this study, we observed model animals using intravital imaging technology and visualized the dynamics of tumor cells during tumor growth and progression. As a result, we extracted the factors that can detect the tumor progression at an early stage and can be applied to the cancer tissue diagnosis in clinical medicine. Moreover, we found that the established evaluation system can be actually applied to human tissue samples.
Amount: ¥4,160,000
Funding type: fellowship
Funder scheme: Grant-in-Aid for Early-Career Scientists
Start date: 2018-04-01
End date: 2020-03-31
Investigator: Takahiro Matsui
Institution: Osaka University
Funded outputs count: 3
Funder award ID: 18K15080
OpenAlex ID: G7944235235