Award

The Neighborhoods Study: Contextual Disadvantage and Alzheimer’s Disease and Related Dementias (ADRD)

Description: NARRATIVE Dementia due to Alzheimer’s disease and related dementias (ADRD) disproportionately impacts racial/ethnic minorities and the socioeconomically disadvantaged; groups more often exposed to neighborhood disadvantage. Prior research supports that neighborhood disadvantage is modifiable and interacts with biological processes to produce disease, yet little is known of its impact on ADRD. This project leverages data within 22 Alzheimer’s Disease Research Centers across the US to conduct the largest study of its kind on social determinants of health in the context of AD and to develop a novel collaborative infrastructure of contextual exposure for future social-biological phenotypic evaluation-- a potential pathway to new therapeutics directly responsive to the NIA mission.
Funding type: research
Funder scheme: R01
Start date: 2021-03-01
End date: 2026-05-31
Investigator: BARBARA BRIGITTA BENDLIN
Institution: UNIVERSITY OF WISCONSIN-MADISON
Funded outputs count: 89
Funder award ID: R01AG070883
OpenAlex ID: G9000914517
2026 · W. Ryan Powell, Eleanna M. Melcher, et al. · Alzheimer s & Dementia
2026 · Sang‐Won Han, Young Ho Park, et al. · Alzheimer s & Dementia
2026 · Eleanna M. Melcher, Amy J.H. Kind · NeuroToxicology
2026 · Valentina Ghisays, Marisa N. Denkinger, et al. · medRxiv
2026 · Mahsa Dolatshahi, Paul K. Commean, et al. · Journal of Alzheimer s Disease · 1
2026 · Justin B. Miller, Tasha Rhoads, et al. · Journal of Alzheimer s Disease · 2
2026 · Raele Donetha Loy, Amy Kind, et al. · Journal of the American Geriatrics Society
2026 · Henrik Zetterberg, Barbara B. Bendlin · Nature · 39
2026 · Nicole Tamvaka, William Scotton, et al. · Brain Communications
2025 · Meredith Pedde, Sara D. Adar, et al. · Environmental Research · 5
2025 · Eun Hye Lee, Yen‐Ning Huang, et al. · Alzheimer s & Dementia · 3
2025 · Grace C. George, Sarah A. Keller, et al. · Alzheimer s & Dementia · 2
2025 · Eleanna M. Melcher, Monica I. Duran, et al. · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
2025 · Shiwei Liu, Yen‐Ning Huang, et al. · Alzheimer s & Dementia · 4
2025 · Sarah A. Keller, Amanda DeWitt, et al. · JAMA Network Open · 8
2025 · Sunnie Reagan, Drew Prescott, et al. · Research in Nursing & Health · 1
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