An association of incidence of pneumonia with dementia, from the point of view of swallowing modality, immune and nutritional status.
Description: Pneumonia-associated morbidity and mortality are increasing with population aging. Morbidity of aspiration pneumonia (AP) occurred in half the institutional residents with advanced dementia. An etiology of AP is silent aspiration due to blunting of the upper respiratory protective reflexes. However, the association of AP-related factors and cerebral degeneration, with the morbidity and mortality of HCAP has not been fully investigated. Furthermore, in clinical settings, untreatable biliary sludge in the gallbladder can be observed in older adults with advanced dementia.Therefore, we executed a cross-sectional, retrospective and prospective-cohort study for the association of AP-related factors and the ability of oral intake with dementia. As results, the deteriorated upper respiratory reflexes, fasting status, malnutrition and atrial filtration were associated with the morbidity and mortality of HCAP and the biliary sludge formation in older adults with dementia.
Amount: ¥4,030,000
Funding type: fellowship
Funder scheme: Grant-in-Aid for Young Scientists (B)
Start date: 2017-04-01
End date: 2021-03-31
Investigator: Takahide Miyamoto
Institution: Kyorin University
Subfield: Speech and Hearing
Field: Health Professions
Domain: Health Sciences
Funded outputs count: 2
Funder award ID: 17K15903
OpenAlex ID: G8021354856