KBASE2: Korean Brain Aging Study, Longitudinal Endophenotypes and Systems Biology
Description: Project Narrative Alzheimer’s disease (AD) and related dementias are a widely recognized major public health problem in the U.S. and globally. The proposed international collaborative project will contribute rich longitudinal biomarker and clinical data and over 1000 whole genome sequences on a Korean cohort to the NIA AD Sequencing Project and related research programs. Well-characterized multi-ethnic genomic data sets are a major priority for AD research. KBASE2 brings a multidisciplinary team together to complete state of the science integrative analyses of the clinical, genetic, brain network and multi-omics data to accelerate the identification of new potential therapeutic targets.
Funder: National Institute on Aging
Funding type: cooperative_agreement
Funder scheme: U01
Start date: 2021-08-15
End date: 2027-07-31
Investigator: DONG YOUNG LEE
Institution: INDIANA UNIVERSITY INDIANAPOLIS
Funded outputs count: 162
Funder award ID: U01AG072177
OpenAlex ID: G9000909353