Award

A European Platform for Translational Cancer Research

Description: Europe has a number of advantages as regards developing translational cancer research, yet there is no clear European strategy to meet the increasing burden posed by cancer. The FP6 Eurocan+Plus project analysed the barriers underlying the increasing fragmentation of cancer research and stressed the need to improve collaboration between basic/preclinical and comprehensive cancer centres (CCCs), institutions in which care and prevention is integrated with research and education. Furthermore, it proposed the creation of a platform of interlinked cancer centres with shared infrastructures and collaborative projects to facilitate rapid advances in knowledge, and their translation into better cancer care. In response to these challenges and in line with the call, EurocanPlatform will work towards the goal of decreasing cancer mortality by dealing with three main areas of strategic research: prevention, early detection and improved treatments. It will build the necessary resources and know-how for the entire research continuum: basic research, early and late translational research, clinical research, epidemiological research, implementation in care and population based outcome research. There will be a strong focus on discovery-driven translational cancer research in five selected tumours: breast, head-neck, lung, malignant melanoma and pancreatic cancer. Joint structures and programmes for early detection will contribute to optimal treatment, and novel prevention research programmes will integrate prevention activities in clinical cancer centres as well as public prevention. Collaborations will also include molecular pathway-driven clinical research supported by joint structures for omics, biobanking and biomarker validation to support clinical trials aimed at enhancing patient benefits by individualised treatments. EurocanPlatform is unique in its nature and represents a commitment from cancer centres to join forces and resources in order to fight cancer.
Amount: €12,000,000
Funding type: grant
Funder scheme: FP7 - NoE
Start date: 2011-01-01
End date: 2016-12-31
Institution: KAROLINSKA INSTITUTET
Funded outputs count: 78
Funder award ID: 260791
OpenAlex ID: G8213305046
2021 · Carolina Reduzzi, Serena Di Cosimo, et al. · Cancers · 52
2020 · PCAWG Transcriptome Core Group, Claudia Calabrese, et al. · Nature · 398
2019 · Lisette M. Cornelissen, Roebi de Bruijn, et al. · Journal of Mammary Gland Biology and Neoplasia · 4
2019 · Leticia De Mattos-Arruda, Stephen-John Sammut, et al. · Cell Reports · 114
2019 · Alexander M. M. Eggermont, Giovanni Apolone, et al. · Molecular Oncology · 50
2018 · Bente Risberg, Dana W.Y. Tsui, et al. · Journal of Molecular Diagnostics · 119
2018 · Michelle L. Churchman, Maoxiang Qian, et al. · Cancer Cell · 205
2018 · Flavie Perrier, Alexei Novoloaca, et al. · Clinical Epigenetics · 52
2018 · Mehdi Touat, Tony Sourisseau, et al. · Journal of Clinical Investigation · 32
2018 · Maurizio Callari, Ankita Sati Batra, et al. · BMC Genomics · 65
2017 · Mónica Álvarez-Fernández, María Sanz-Flores, et al. · Cell Death and Differentiation · 86
2017 · Masoud Babaei, Yesilda Balavarca, et al. · International Journal of Cancer · 48
2017 · Carol MacKintosh · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
2017 · Ugis Sarkans, Mikhail Gostev, et al. · Nucleic Acids Research · 231
2017 · Lucía Simón-Carrasco, Osvaldo Graña, et al. · Genes & Development · 59
2017 · Christopher Buccitelli, Lorena Salgueiro, et al. · Genome Research · 63
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