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Award

Embryo implantation and Placental Development

Amount: A$686,700
Funding type: fellowship
Funder scheme: Research Fellowship
Start date: 2013-01-01
End date: 2017-12-31
Investigator: A/Pr Nie
Institution: Monash University
Funded outputs count: 20
Funder award ID: 1041835
OpenAlex ID: G8232868792
Second and third trimester serum levels of HtrA1 in pregnancies affected by pre-eclampsia
2021 · Sasha Skinner, Daniel L. Rolnik, et al. · Placenta · 4
Podocalyxin is a key negative regulator of human endometrial epithelial receptivity for embryo implantation
2021 · Sarah G Paule, Sophea Heng, et al. · Human Reproduction · 47
Second‐ and third‐trimester serum levels of growth‐differentiation factor‐15 in prediction of pre‐eclampsia
2020 · D. Wertaschnigg, D. L. Rolnik, et al. · Ultrasound in Obstetrics and Gynecology · 24
Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes
2019 · Yao Wang, Rebecca Lim, et al. · Placenta · 24
HtrA4 may play a major role in inhibiting endothelial repair in pregnancy complication preeclampsia
2019 · Yao Wang, Rebecca Lim, et al. · Scientific Reports · 30
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HtrA1 alters endothelial tube formation characteristics in an in vitro model
2019 · Harmeet Singh, Guiying Nie · bioRxiv (Cold Spring Harbor Laboratory)
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High levels of HtrA4 detected in preeclamptic circulation may disrupt endothelial cell function by cleaving the main VEGFA receptor KDR
2019 · Yao Wang, Mylinh La, et al. · The FASEB Journal · 19
Elevated protease HtrA4 in the maternal circulation of preeclampsia may contribute to endothelial barrier disruption by cleaving key junctional protein VE-cadherin
2019 · Esther Tseng, Sonia Soo Yee Teoh, et al. · Placenta · 23
Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood
2017 · Ying Li, Lois A. Salamonsen, et al. · Scientific Reports · 12
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Multiple Soluble TGF-β Receptors in Addition to Soluble Endoglin Are Elevated in Preeclamptic Serum and They Synergistically Inhibit TGF-β Signaling
2017 · Yao Wang, Qi Chen, et al. · The Journal of Clinical Endocrinology & Metabolism · 16
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The significance of post-translational removal of α-DG-N in early stage endometrial cancer development
2017 · Sophea Heng, Jemma Evans, et al. · Oncotarget · 5
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HtrA3 Isoform–Specific ELISAs for Early Detection of Preeclampsia
2016 · Yao Wang, Ying Li, et al. · SLAS DISCOVERY · 14
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High levels of HtrA4 observed in preeclamptic circulation drastically alter endothelial gene expression and induce inflammation in human umbilical vein endothelial cells
2016 · Yao Wang, Guiying Nie · Placenta · 29
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Measuring PC activity in endocervical swab may provide a simple and non-invasive method to detect endometrial cancer in post-menopausal women
2016 · Sophea Heng, Andrew N. Stephens, et al. · Oncotarget · 12
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Serum levels of GDF15 are reduced in preeclampsia and the reduction is more profound in late-onset than early-onset cases
2016 · Qi Chen, Yao Wang, et al. · Cytokine · 48
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Total PC Activity Is Increased in Uterine Lavage of Post-Menopausal Endometrial but Not Ovarian Cancer Patients
2016 · Sophea Heng, Andrew N. Stephens, et al. · Journal of Cancer · 3
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Corrigenda
2015 · The Journal of Clinical Endocrinology & Metabolism · 5
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Serum HtrA1 is differentially regulated between early-onset and late-onset preeclampsia
2015 · Sonia Soo Yee Teoh, Min Zhao, et al. · Placenta · 37
Activity-Modulating Monoclonal Antibodies to the Human Serine Protease HtrA3 Provide Novel Insights into Regulating HtrA Proteolytic Activities
2014 · Harmeet Singh, Tracy L. Nero, et al. · PLoS ONE · 24
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Small Molecule Proprotein Convertase Inhibitors for Inhibition of Embryo Implantation
2013 · Huiting Ho, Harmeet Singh, et al. · PLoS ONE · 19
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