Award

DK117147

Funder: National Institute of Diabetes and Digestive and Kidney Diseases

Funded outputs count: 15

Funder award ID: DK117147

OpenAlex ID: G8399730701

CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets

2024 · Xiangni Wu, Pin-I Chen, et al. · Frontiers in Immunology · 13

Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes

2023 · Udi Ehud Knebel, Shani Peleg, et al. · Cell Metabolism · 50

Genetic risk converges on regulatory networks mediating early type 2 diabetes

2023 · John T. Walker, Diane C. Saunders, et al. · Nature · 88

Exocrine Pancreas in Type 1 and Type 2 Diabetes: Different Patterns of Fibrosis, Metaplasia, Angiopathy, and Adiposity

2023 · Jordan J. Wright, Adel Eskaros, et al. · Diabetes · 36

Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss

2023 · Tiffany M. Richardson, Diane C. Saunders, et al. · American Journal of Physiology-Endocrinology and Metabolism · 15

Hyperaminoacidemia induces pancreatic α cell proliferation via synergism between the mTORC1 and CaSR-Gq signaling pathways

2023 · Yulong Gong, Bingyuan Yang, et al. · Nature Communications · 29

Combinatorial transcription factor profiles predict mature and functional human islet α and β cells

2021 · Shristi Shrestha, Diane C. Saunders, et al. · JCI Insight · 45

Debates in Pancreatic Beta Cell Biology: Proliferation Versus Progenitor Differentiation and Transdifferentiation in Restoring β Cell Mass

2021 · Erick Spears, Ioannis Serafimidis, et al. · Frontiers in Endocrinology · 46

Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration

2021 · Diane C. Saunders, Kristie I. Aamodt, et al. · npj Regenerative Medicine · 36

Faculty Opinions recommendation of Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets.

2021 · Richard J Naftalin · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature

Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets

2021 · May-Yun Wang, E. Danielle Dean, et al. · Proceedings of the National Academy of Sciences · 47

RIPK3-mediated inflammation is a conserved β cell response to ER stress

2020 · Bingyuan Yang, Lisette A. Maddison, et al. · Science Advances · 59

Dapagliflozin Does Not Directly Affect Human α or β Cells

2020 · Chunhua Dai, John T Walker, et al. · Endocrinology · 15

Integrated human pseudoislet system and microfluidic platform demonstrate differences in GPCR signaling in islet cells

2020 · John T. Walker, Rachana Haliyur, et al. · JCI Insight · 58

A Primary Role for α-Cells as Amino Acid Sensors

2019 · E. Danielle Dean · Diabetes · 94