Award

BC141351

Funder: National Institutes of Health

Funded outputs count: 15

Funder award ID: BC141351

OpenAlex ID: G8413211002

Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility

2024 · Rosalyn W Sayaman, Masaru Miyano, et al. · eLife · 22

Functional delineation of the luminal epithelial microenvironment in breast using cell-based screening in combinatorial microenvironments

2023 · Tiina A. Jokela, Mark A. Dane, et al. · Cellular Signalling · 1

Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells

2023 · Parijat Senapati, Masaru Miyano, et al. · Genome Research · 23

Sustained postconfluent culture of human mammary epithelial cells enriches for luminal and c-Kit+ subtypes

2023 · Michael E. Todhunter, Masaru Miyano, et al. · Breast Cancer Research · 2

Protocol for computationally evaluating the loss of stoichiometry and coordinated expression of proteins

2022 · Stefan Hinz, Michael E. Todhunter, et al. · STAR Protocols

Evidence for accelerated aging in mammary epithelia of women carrying germline BRCA1 or BRCA2 mutations

2021 · Sundus F. Shalabi, Masaru Miyano, et al. · Nature Aging · 79

Deep proteome profiling of human mammary epithelia at lineage and age resolution

2021 · Stefan Hinz, Antigoni Manousopoulou, et al. · iScience · 11

Breast-Specific Molecular Clocks Comprised of ELF5 Expression and Promoter Methylation Identify Individuals Susceptible to Cancer Initiation

2021 · Masaru Miyano, Rosalyn W. Sayaman, et al. · Cancer Prevention Research · 19

Epigenetic changes with age primes mammary luminal epithelia for cancer initiation

2021 · Rosalyn W. Sayaman, Masaru Miyano, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 10

Contributions of Yap and Taz dysfunction to breast cancer initiation, progression, and aging‐related susceptibility

2020 · Tara Fresques, Mark A. LaBarge · Aging and Cancer · 9

Normal mammary epithelia accumulate DNA methylation changes with age that are consistent with breast cancer methylomes

2020 · Parijat Senapati, Masaru Miyano, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4

Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance

2018 · Tiina A. Jokela, Agnete S. T. Engelsen, et al. · Frontiers in Cell and Developmental Biology · 25

High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia

2018 · Fanny A. Pelissier Vatter, Denis Schapiro, et al. · Cell Reports · 58

Characterizing cellular mechanical phenotypes with mechano-node-pore sensing

2018 · Junghyun Kim, Sewoon Han, et al. · Microsystems & Nanoengineering · 64

Age-related gene expression in luminal epithelial cells is driven by a microenvironment made from myoepithelial cells

2017 · Masaru Miyano, Rosalyn W. Sayaman, et al. · Aging · 37