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SATURN3

Funded outputs count: 51
Funder award ID: SATURN3
OpenAlex ID: G8482385449
Key regulatory elements of the TGFβ–LRRC15 axis predict disease progression and immunotherapy resistance across cancer types
2026 · Michael Cheng, Claire M. Storey, et al. · Proceedings of the National Academy of Sciences
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Targeting Kras signalling in a Trp53/KrasG12D mouse and organoid model inhibits Barrett esophagus to gastroesophageal adenocarcinoma progression
2026 · Akanksha Anand, Linus R. Schoemig, et al. · Scientific Reports
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Divergent c-MYC Expression Patterns in NET and NEC: Insights from a Multicentre Cohort of 1380 Neuroendocrine Neoplasms
2026 · Maxime Schmitt, Katharina Ofner, et al. · Endocrine Pathology · 1
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Oncofetal cell states: cell plasticity drives invasion in premetastatic colorectal tumors
2026 · Mahmoud N. A. Amer, Florian R. Greten · Signal Transduction and Targeted Therapy
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Beyond benchmarking: an expert-guided consensus approach to spatially aware clustering
2026 · Jieran Sun, Kirti Biharie, et al. · Nature Methods · 6
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Disagreement between demultiplexing methods reveals structured cell quality gradients in multiplexed single-cell data
2026 · Ezgi Sen, Simon Steiger, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Multifaceted immune resistance landscapes in human oligodendrocytes protect against cytotoxic T cells and are dysregulated in MS brain cell subsets
2026 · Ayse Nur Menevse, Abir Hussein, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Clinical and Molecular Evaluation of HER2-Low and HER2-Ultralow Breast Cancer in the Penelope-B Clinical Trial Cohort
2026 · Carsten Denkert, Sivaramakrishna Rachakonda, et al. · Modern Pathology · 3
BCL-xL as a therapeutic target in cetuximab-refractory colorectal cancer
2026 · Stella Asmanidou, Julia Thiel, et al. · Cell Death and Disease · 1
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Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial
2025 · Dominic Denk, Anurag Singh, et al. · Nature Aging · 50
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Development of a leucine-rich repeat-containing protein 15-targeted radio-immunotheranostic approach to deplete pro-tumorigenic mechanisms and immunotherapy resistance
2025 · Claire M. Storey, Mohamed Altai, et al. · Signal Transduction and Targeted Therapy · 10
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Adaptive resistance to SHP2-based vertical RAS-pathway inhibition in pancreatic cancer involves multifaceted routes towards dedifferentiation
2025 · Xun Chen, Steffen Johannes Keller, et al. · medRxiv
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Detecting and quantifying clonal selection in somatic stem cells
2025 · Verena Körber, Niels Asger Jakobsen, et al. · Nature Genetics · 8
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Comparison of spatial transcriptomics technologies using tumor cryosections
2025 · Anne Rademacher, Alik Huseynov, et al. · Genome biology · 35
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Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time
2025 · Katja Wittenzellner, Manuel Lengl, et al. · JCI Insight · 8
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Large vesicles from ageing neutrophils: novel safeguards for the resolution of inflammation
2025 · Christopher Dietz-Fricke, Florian R. Greten · Signal Transduction and Targeted Therapy · 1
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Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma
2025 · Melissa Barroux, Jacob Househam, et al. · Nature Cancer · 20
A floating collagen matrix triggers ring formation and stemness characteristics in human colorectal cancer organoids
2025 · Daniel Gerhard Wimmers, Kerstin Huebner, et al. · Pathology - Research and Practice · 6
Isolation of a tumor neoantigen specific CD8+ TCR from a skin biopsy of a vaccination site
2025 · Maria Paula Roberti, Pornpimol Charoentong, et al. · OncoImmunology · 2
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Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence
2025 · Julius Keyl, Philipp Keyl, et al. · Nature Cancer · 68
Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response
2025 · Stefanie Höfer, Larissa Frasch, et al. · Molecular Systems Biology · 27
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Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma
2024 · Aristeidis Papargyriou, Mulham Najajreh, et al. · Nature Biomedical Engineering · 45
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Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer
2024 · Lisa Veghini, Davide Pasini, et al. · Nature Communications · 43
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Molecular adaptation to neoadjuvant immunotherapy in triple-negative breast cancer
2024 · Carsten Denkert, Andreas Schneeweiss, et al. · Cell Reports Medicine · 23
Minimally invasive determination of pancreatic ductal adenocarcinoma ( PDAC ) subtype by means of circulating cell‐free RNA
2024 · Martin Metzenmacher, Gregor Zaun, et al. · Molecular Oncology · 6
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