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N013255/1

Funded outputs count: 24
Funder award ID: N013255/1
OpenAlex ID: G8501662357
DNA methylation patterns in the frontal lobe white matter of multiple system atrophy, Parkinson’s disease, and progressive supranuclear palsy: a cross-comparative investigation
2024 · Megha Murthy, Katherine Fodder, et al. · Acta Neuropathologica · 8
Inhibition of insulin-degrading enzyme in human neurons promotes amyloid-β deposition
2023 · Helen A. Rowland, Samuel R. Moxon, et al. · Neuronal Signaling · 9
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The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration
2023 · Katherine Fodder, Rohan de Silva, et al. · Acta Neuropathologica Communications · 18
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Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease GBA-N370S dopamine neurons
2023 · Helle Bogetofte, Brent J. Ryan, et al. · Cell Reports · 47
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Epigenetic age acceleration is associated with oligodendrocyte proportions in MSA and control brain tissue
2022 · Megha Murthy, Gemma Shireby, et al. · Neuropathology and Applied Neurobiology · 16
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Pathological substrate of memory impairment in multiple system atrophy
2022 · Yasuo Miki, Kunikazu Tanji, et al. · Neuropathology and Applied Neurobiology · 24
Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons
2021 · Leonard C. Steg, Gemma L. Shireby, et al. · Molecular Brain · 34
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In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages
2021 · Hazel Hall-Roberts, Elena Di Daniel, et al. · Journal of Visualized Experiments · 7
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In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages
2021 · Hazel Hall-Roberts, Elena Di Daniel, et al. · Journal of Visualized Experiments · 8
Identification of multiple system atrophy mimicking Parkinson’s disease or progressive supranuclear palsy
2021 · Yasuo Miki, Eiki Tsushima, et al. · Brain · 54
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MOBP and HIP1 in multiple system atrophy: New α‐synuclein partners in glial cytoplasmic inclusions implicated in the disease pathogenesis
2020 · Conceição Bettencourt, Yasuo Miki, et al. · Neuropathology and Applied Neurobiology · 18
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TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages
2020 · Hazel Hall-Roberts, Devika Agarwal, et al. · Alzheimer s Research & Therapy · 62
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Novel Epigenetic Clock for Fetal Brain Development Predicts Fetal Epigenetic Age for iPSCs and iPSC-Derived Neurons.
2020 · Leonard C Steg, Gemma L Shireby, et al.
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Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons
2020 · Leonard C. Steg, Gemma L. Shireby, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3
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Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936
2020 · Jamie Toombs, Lindsay Panther, et al. · Stem Cell Research · 17
Epigenomics and transcriptomics analyses of multiple system atrophy brain tissue supports a role for inflammatory processes in disease pathogenesis
2020 · Conceição Bettencourt, Ignazio S. Piras, et al. · Acta Neuropathologica Communications · 7
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Extracellular Vesicles Isolated from Human Induced Pluripotent Stem Cell-Derived Neurons Contain a Transcriptional Network
2020 · David A. Hicks, Alys C. Jones, et al. · Neurochemical Research · 19
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LRRK2 Is Recruited to Phagosomes and Co-recruits RAB8 and RAB10 in Human Pluripotent Stem Cell-Derived Macrophages
2020 · Heyne Lee, Rowan Flynn, et al. · Stem Cell Reports · 81
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The Alzheimer’s disease protective P522R variant of PLCG2 , consistently enhances stimulus-dependent PLCγ2 activation, depleting substrate and altering cell function
2020 · Emily Maguire, Georgina E. Menzies, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
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Blended alginate/collagen hydrogels promote neurogenesis and neuronal maturation
2019 · Samuel R. Moxon, Nicola J. Corbett, et al. · Materials Science and Engineering C · 143
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Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets
2019 · Sohaib Nizami, Hazel Hall‐Roberts, et al. · British Journal of Pharmacology · 147
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Modelling Sporadic Alzheimer’s Disease Using Induced Pluripotent Stem Cells
2018 · Helen A. Rowland, Nigel M. Hooper, et al. · Neurochemical Research · 37
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Human stem cell–derived astrocytes replicate human prions in a PRNP genotype–dependent manner
2017 · Zuzana Krejciova, James Alibhai, et al. · The Journal of Experimental Medicine · 92
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Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages
2017 · Walther Haenseler, Federico Zambon, et al. · Scientific Reports · 117
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