Defining the Role of Adipogenesis in Age-Associated Adiposity
Description: PROJECT NARRATIVE People over age 65 typically suffer from visceral adiposity, which accelerates aging by promoting insulin resistance, cardiovascular dysfunction, and many other chronic health conditions, significantly shortening healthspan and lifespan. We recently discovered that the generation of new fat cells is the major contributor of age-associated adiposity, and we propose to study when, where, and why does the making of new fat cells take place during aging. Successful completion of the proposed research will provide new therapeutic avenues for the prevention and treatment of age-associated adiposity and its related chronic diseases, ultimately promoting longevity and healthy aging.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2020-05-15
End date: 2026-04-30
Investigator: QIONG ANNABEL WANG
Institution: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Funded outputs count: 9
Funder award ID: R01AG063854
OpenAlex ID: G7388308262