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Wuhan Interaction with Stockholm Evidence-based Research (WISER) project on health perspectives in the older population facing the SARS-CoV-2 outbreak

Description: The SARS-CoV-2 outbreak severely affected the cities of Wuhan and Stockholm in 2020. The most affected was the old segment of the population, where thousands died in hospitals and in elderly care homes. Different strategies were implemented to protect the population; from lockdown in Wuhan to social distancing in Stockholm. The aim of the WISER (Wuhan Interaction with Stockholm Evidence-based Research) project is to analyze health perspectives of the old population during the COVID-19 epidemic. We will analyze public health interventions on disease spreading in the old population using a Bayesian inference framework. In addition, we will identify COVID-19 risk factors in elderly living in care homes and in geriatric patients admitted to hospital. What risk factors identify vulnerable individuals in need of more advanced care? Moreover, we will follow up geriatric patients and analyze their long-term health consequences after COVID-19 infection. As we partly use selected samples in the analyses, we will also develop methods to account for sampling bias.The research team from China and Sweden brings together experts in infectious disease epidemiology, biostatistics, gerontologists knowledgeable on frailty, as well as clinical geriatricians important for collecting clinical data. The project covers three years, with shared responsibility for the aims. Together, we will move the forefront in COVID-19 epidemiology of the most affected old individuals.
Amount: SEK 9,000,000
Funding type: research
Funder scheme: Project grant
Start date: 2021-01-01
End date: 2023-12-31
Investigator: Sara Hägg
Institution: Karolinska Institutet
Funded outputs count: 28
Funder award ID: 2020-06101
OpenAlex ID: G8628914069
2025 · Christopher E. McMurran, Ida K. Karlsson, et al. · Aging Cell · 3
2025 · Jonathan K. L. Mak, Kathryn Choon Beng Tan, et al. · Journal of Cachexia Sarcopenia and Muscle · 5
2025 · Thaís Lopes De Oliveira, Arianna March, et al. · Clinical Epigenetics · 1
2024 · Daniel Wikström Shemer, Shayan Mostafaei, et al. · GeroScience · 21
2024 · Jonathan K. L. Mak, Asmus Cosmos Skovgaard, et al. · Aging Cell · 12
2024 · Bahira Shahim, Hong Xu, et al. · European Heart Journal - Cardiovascular Pharmacotherapy · 15
2023 · Laura Kananen, Christian Molnár, et al. · Health Science Reports · 3
2023 · Jonathan K L Mak, Ida K Karlsson, et al. · The Journals of Gerontology Series A · 33
2023 · Anna Giani, Hong Xu, et al. · Journal of the American Medical Directors Association · 1
2023 · Jonathan K. L. Mak, Christopher E. McMurran, et al. · British Journal of Cancer · 168
2023 · Chenxi Qin, Lina-Marcela Diaz-Gallo, et al. · European Journal of Epidemiology · 34
2023 · Jonathan K. L. Mak, Ralf Kuja-Halkola, et al. · GeroScience · 28
2023 · Adil Supiyev, Robert Karlsson, et al. · Neurobiology of Aging · 5
2022 · Saara Marttila, Hely Tamminen, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
2022 · Jonathan K L Mak, Sara Hägg, et al. · The Journals of Gerontology Series A · 30
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