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32170652
Funder:
National Natural Science Foundation of China
Funded outputs count:
19
Funder award ID:
32170652
OpenAlex ID:
G8936027694
Quantifying epigenetic reprogramming and cellular plasticity in preneoplastic lesions reveals dedifferentiation as a key precancer hallmark
2026
·
Jason Tham Han Kiat
, Andrew E. Teschendorff
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes
2025
·
Xiaolong Guo
, Josephine A. Robertson
, et al.
·
Advanced Science
·
7
PDF
Optimizing effect sizes and specificity trumps machine learning when building DNA methylation reference panels for cell-type deconvolution
2025
·
Xiaolong Guo
, Andrew E Teschendorff
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Unified high-resolution immune cell fraction estimation in blood tissue from birth to old age
2025
·
Xiaolong Guo
, Mahnoor Sulaiman
, et al.
·
Genome Medicine
·
10
PDF
Epigenetic clocks and inflammaging: pitfalls caused by ignoring cell-type heterogeneity
2025
·
Xiaolong Guo
, Andrew E. Teschendorff
·
GeroScience
·
13
PDF
Cell-type-specific subtyping of epigenomes improves prognostic stratification of cancer
2025
·
Qi Luo
, Andrew E. Teschendorff
·
Genome Medicine
·
6
PDF
Interpretable deep learning of single-cell and epigenetic data reveals novel molecular insights in aging
2025
·
Zhi-Peng Li
, Zhaozhen Du
, et al.
·
Scientific Reports
·
22
PDF
Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution
2024
·
Huige Tong
, Xiaolong Guo
, et al.
·
Aging
·
34
PDF
An improved epigenetic counter to track mitotic age in normal and precancerous tissues
2024
·
Tianyu Zhu
, Huige Tong
, et al.
·
Nature Communications
·
27
Quantifying the stochastic component of epigenetic aging
2024
·
Huige Tong
, Varun B. Dwaraka
, et al.
·
Nature Aging
·
76
Analysis of blood methylation quantitative trait loci in East Asians reveals ancestry-specific impacts on complex traits
2024
·
Qianqian Peng
, Xinxuan Liu
, et al.
·
Nature Genetics
·
41
PDF
On epigenetic stochasticity, entropy and cancer risk
2024
·
Andrew E. Teschendorff
·
Philosophical Transactions of the Royal Society B Biological Sciences
·
25
A meta-analysis of immune-cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes
2023
·
Qi Luo
, Varun B. Dwaraka
, et al.
·
Genome Medicine
·
64
PDF
Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data
2023
·
Alok K. Maity
, Andrew E. Teschendorff
·
Nature Communications
·
11
PDF
Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data
2023
·
Alok K. Maity
, Andrew E. Teschendorff
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
Data from Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression
2023
·
Tianyuan Liu
, Xuan Zhao
, et al.
Data from Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression
2023
·
Tianyuan Liu
, Xuan Zhao
, et al.
Distance covariance entropy reveals primed states and bifurcation dynamics in single-cell RNA-Seq data
2022
·
Qi Luo
, Alok K. Maity
, et al.
·
iScience
·
5
PDF
Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression
2022
·
Tianyuan Liu
, Xuan Zhao
, et al.
·
Cancer Research
·
23
PDF
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