Aerobic Fitness, Mitochondrial Function, and Fatty Liver Disease.
Description: Intrinsic aerobic capacity and exercise have a profound impact on the development and treatment of fatty liver but mechanisms of action remain unknown. The proposed studies seek to examine if intrinsic aerobic capacity and exercise impacts susceptibility for fatty liver through enhanced mitochondrial function, bile acid metabolism, and epigenetics. Outcomes will outline potential therapeutic targets for treating fatty liver.
Funding type: research
Funder scheme: R01
Start date: 2019-07-01
End date: 2024-06-30
Investigator: JOHN P THYFAULT
Institution: UNIVERSITY OF KANSAS MEDICAL CENTER
Funded outputs count: 27
Funder award ID: R01DK121497
OpenAlex ID: G1444203813