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Procurement and Characterization of Postmortem Brain Tissue

Funding type: intramural
Funder scheme: ZIC
Investigator: STEFANO MARENCO
Institution: NATIONAL INSTITUTE OF MENTAL HEALTH
Funded outputs count: 54
Funder award ID: ZICMH002903
OpenAlex ID: G9000861083
Single-nucleus transcriptome-wide association study of human brain disorders
2026 · Sanan Venkatesh, Roman Kosoy, et al. · Nature · 7
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Single-nucleus atlas of cell-type specific genetic regulation in the human brain
2026 · Biao Zeng, Hui Yang, et al. · Nature Genetics · 5
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AI-based characterization of Alzheimer’s disease phenotypes from population-scale single-cell data
2026 · Chenfeng He, Athan Z. Li, et al. · Nature Medicine · 1
Single-cell atlas of transcriptomic vulnerability across brain disorders
2026 · Donghoon Lee, Mikaela Koutrouli, et al. · Nature · 5
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Lifespan single-cell transcriptomic atlas of the human prefrontal cortex
2026 · Hui Yang, Tereza Clarence, et al. · Nature · 3
Personalized single-cell transcriptomics reveals molecular diversity in Alzheimer’s disease
2026 · Pramod Bharadwaj Chandrashekar, Sayali Anil Alatkar, et al. · Nature Communications · 1
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Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer’s disease
2026 · Donghoon Lee, James M. Vicari, et al. · Nature Genetics · 22
Long-read sequencing maps transposable element variation and its regulatory and epigenetic effects in the human brain
2026 · Alexis Ayuketah, Melissa Meredith, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Region-specific transcriptional signatures of brain aging in the absence of neuropathology at the single-cell level
2026 · Monica E. Mesecar, Megan F. Duffy, et al. · npj Aging · 24
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Sex effects on gene expression across the human cerebral cortex at cell type resolution
2026 · Alex R. DeCasien, Pavan Auluck, et al. · Science · 14
Single-nucleus multiome analysis in the human prefrontal cortex identifies gene expression and cis-regulatory elements associated with aging
2026 · Adam Catching, Cory A. Weller, et al. · Cell Reports · 3
Gene regulatory programs of cognitive resilience and pathogenesis in Alzheimer’s disease
2026 · Collin Spencer, N.M. Prashant, et al. · medRxiv
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A transcriptomic dimension of neuronal and immune gene programs within the subgenual anterior cingulate cortex in schizophrenia
2026 · Rachel L. Smith, Agoston Mihalik, et al. · Translational Psychiatry · 1
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Single‐cell atlas of transcriptomic vulnerability across multiple neurodegenerative and neuropsychiatric diseases
2025 · Donghoon Lee, Mikaela Koutrouli, et al. · Alzheimer s & Dementia · 20
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Brain region and cell type-specific DNA methylation profiles in association with ADHD
2025 · Mandy Meijer, Gustavo Sudre, et al. · Scientific Reports · 9
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Long-Read epigenetic clocks identify improved brain aging predictions
2025 · Spencer M. Grant, Sarah J. Eger, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Associations Between Fatty Acid Levels in Human Blood and Trigeminovascular Tissues
2025 · Daisy Zamora, Mark S. Horowitz, et al. · Lipids · 1
Investigating the role of melatonin in bipolar disorder using transcriptomics
2025 · Heather K. Macpherson, Trang T. T. Truong, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Postmortem tissue biomarkers of menopausal transition
2025 · Maria Tickerhoof, Heining Cham, et al. · Molecular Psychiatry · 5
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Brain network and blood transcriptomic correlations underpin psychopathological phenotypes: A Preliminary Study
2025 · Dennis Wylie, Dhivya Arasappan, et al. · medRxiv
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Population-scale cross-disorder atlas of the human prefrontal cortex at single-cell resolution
2025 · John F. Fullard, Prashant NM, et al. · Scientific Data · 17
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An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration
2025 · Matthew J. Leventhal, Camila A. Zanella, et al. · Nature Communications · 28
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A neuro-immune axis of transcriptomic dysregulation within the subgenual anterior cingulate cortex in schizophrenia
2025 · Rachel L. Smith, Agoston Mihalik, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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βIV spectrin abundancy, cellular distribution and sensitivity to AKT/GSK3 regulation in schizophrenia
2025 · Jessica Di Re, Michela Marini, et al. · Molecular Psychiatry · 2
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Haplotype-Resolved Long-Read Sequencing in Hundreds of Diverse Brains Identifies Structural Variant Impacts on Expression and Allele-Specific Methylation
2024 · Melissa Meredith, Kensuke Daida, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 16
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