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AG043376

Funded outputs count: 40
Funder award ID: AG043376
OpenAlex ID: G9000031524
Novel Flavonoid Senotherapeutics Identified by Phenotypic Drug Discovery Reduce Senescence and Improve Multiple Markers of Healthspan
2026 · Lei Justan Zhang, Rahagir Salekeen, et al. · Aging Cell
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Slowing intervertebral disc aging in mice through long-term systemic treatment with the senolytic BCL-2/BCL-xL proteolysis targeting chimera (PROTAC) 753b
2026 · Peter G. Alexander, Bowen Yan, et al. · Aging · 1
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Space radiation induces distinct senescent phenotypes: Implications for space travel
2025 · Louise E. Pitcher, Bipasha Mukherjee, et al. · npj Aging · 4
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Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair
2025 · Paul Robbins, Lei Zhang, et al. · Research Square · 5
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Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair
2025 · Lei Justan Zhang, Osama Elsallabi, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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The Fifth Annual Symposium of the Midwest Aging Consortium
2024 · Brenda F Reader, Lorena Rosas, et al. · The Journals of Gerontology Series A
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Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities
2023 · Prashanta Silwal, Allison M. Nguyen-Thai, et al. · Biomolecules · 218
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Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy
2023 · Chathurika Henpita, Rajesh Vyas, et al. · Aging Cell · 29
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Cellular Senescence in Obesity and Associated Complications: a New Therapeutic Target
2022 · Akilavalli Narasimhan, Rafael R. Flores, et al. · Current Diabetes Reports · 38
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Cellular senescence: a key therapeutic target in aging and diseases
2022 · Lei Zhang, Louise E. Pitcher, et al. · Journal of Clinical Investigation · 632
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Immune Senescence, Immunosenescence and Aging
2022 · Kyoo-A Lee, Rafael R. Flores, et al. · Frontiers in Aging · 283
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Extending human healthspan and longevity: a symposium report
2021 · Loren M. DeVito, Nir Barzilai, et al. · Annals of the New York Academy of Sciences · 58
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Role of Cellular Senescence in Type II Diabetes
2021 · Akilavalli Narasimhan, Rafael R Flores, et al. · Endocrinology · 133
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Hitting the Bullseye: Are extracellular vesicles on target?
2020 · Nicole Noren Hooten, María Yáñez‐Mó, et al. · Journal of Extracellular Vesicles · 22
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
2020 · Paul D. Robbins, Diana Jurk, et al. · The Annual Review of Pharmacology and Toxicology · 343
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Resilience in aging and age-related disease. Abstracts from the 2019 Barshop Conference on Aging
2020 · Warren Ladiges, Yuji Ikeno, et al. · Aging Pathobiology and Therapeutics · 1
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Hydrogen sulfide stimulates xanthine oxidoreductase conversion to nitrite reductase and formation of NO
2020 · Sibile Pardue, Gopi K. Kolluru, et al. · Redox Biology · 38
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Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice
2020 · Matthew J. Yousefzadeh, Jing Zhao, et al. · Aging Cell · 331
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Faculty Opinions recommendation of Senolytics improve physical function and increase lifespan in old age.
2019 · Rebecca Mason · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice
2019 · Yohei Kawakami, William S. Hambright, et al. · Molecular Therapy — Methods & Clinical Development · 48
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The impact of xanthine oxidase (XO) on hemolytic diseases
2018 · Heidi M. Schmidt, Eric E. Kelley, et al. · Redox Biology · 131
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Fisetin is a senotherapeutic that extends health and lifespan
2018 · Matthew J. Yousefzadeh, Yi Zhu, et al. · EBioMedicine · 1,034
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Faculty Opinions recommendation of Senolytics improve physical function and increase lifespan in old age.
2018 · Jin-Xiong She, Cong-Yi Wang · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging
2018 · Aditi U. Gurkar, Andria R. Robinson, et al. · Redox Biology · 43
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Faculty Opinions recommendation of The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
2018 · Robert Casper · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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