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Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's Disease

Description: PUBLIC HEALTH RELEVANCE: This study will integrate postmortem brain examination into an ongoing cohort study of risk factors for AD in older Blacks and compare them to matched Whites to identify racial differences in the pathologic substrates of AD. These data are critical t reduce disparities and the burden of AD and cognitive decline in a rapidly growing and understudied population.
Funding type: research
Funder scheme: RF1
Start date: 2004-09-30
End date: 2021-08-31
Investigator: LISA L BARNES
Institution: RUSH UNIVERSITY MEDICAL CENTER
Field: Medicine
Funded outputs count: 120
Funder award ID: RF1AG022018
OpenAlex ID: G3004476995
MARBLE: An in vivo MRI marker of limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change (LATE‐NC)
2026 · Mahir Tazwar, Arnold M. Evia, et al. · Alzheimer s & Dementia
Brain morphometry patterns in the presence of Alzheimer's disease and/or LATE neuropathologic changes
2026 · Khalid Saifullah, Abdur Raquib Ridwan, et al. · Alzheimer s & Dementia
The role of vascular risk factors in white matter tract microstructure: a multi‐cohort study in older adults
2026 · James D. LeFevre, Yukti Vyas, et al. · Alzheimer s & Dementia
RBFOX1 association with age at onset of Alzheimer's disease
2026 · Laura Xicota, Rong Cheng, et al. · Alzheimer s & Dementia
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Pain, Depression, and Functional Outcomes Among Older Adults Who Use Cannabis or Opioid Analgesics for Chronic Pain Conditions
2025 · Jonathan H. Aebischer, Lyndsey M. Anderson, et al. · Clinical Gerontologist · 2
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The dynamics of cognitive decline toward Alzheimer's disease progression: Results from ADSP‐PHC's harmonized cognitive composites
2025 · Kaidi Kang, Panpan Zhang, et al. · Alzheimer s & Dementia · 8
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Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study
2025 · Md Tahmid Yasar, Arnold M. Evia, et al. · Annals of Clinical and Translational Neurology · 1
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Change in transverse relaxation rates ( R2 ) and change in cognition for older African Americans
2024 · Melissa Lamar, Konstantinos Arfanakis, et al. · Human Brain Mapping · 2
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Loneliness, cerebrovascular and Alzheimer's disease pathology, and cognition
2024 · Patrick Lao, Christina B. Young, et al. · Alzheimer s & Dementia · 17
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Associations of Nativity and the Role of the Hispanic Paradox on the Cognitive Health of Older Latinos Living in the United States
2024 · Jocelyn Jaen, Francine Grodstein, et al. · Journal of Alzheimer s Disease · 4
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Whole genome‐wide sequence analysis of long‐lived families (Long‐Life Family Study) identifies MTUS2 gene associated with late‐onset Alzheimer's disease
2024 · Laura Xicota, Stephanie Cosentino, et al. · Alzheimer s & Dementia · 16
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Delayed primacy recall performance predicts post mortem Alzheimer's disease pathology from unimpaired ante mortem cognitive baseline
2024 · Davide Bruno, Kristina M. Gicas, et al. · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · 9
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Changes in Body Mass Index and Incident Mild Cognitive Impairment Among African American Older Adults
2023 · Adrienne T Aiken-Morgan, Ana W Capuano, et al. · The Journals of Gerontology Series A · 10
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Changes in an in-vivo classifier of ARTerioloSclerosis (ARTS) with simultaneous change in cognition for older African Americans
2023 · Melissa Lamar, Konstantinos Arfanakis, et al. · Neurobiology of Aging · 6
Differences in Life Space Activity Patterns Between Older Adults With Mild Cognitive Impairment Living Alone or as a Couple: Cohort Study Using Passive Activity Sensing
2023 · Marijn Muurling, Wan-Tai M Au-Yeung, et al. · JMIR Aging · 7
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Identification of Dementia in Medicare Claims Compared to Rigorous Clinical Assessments in African Americans
2023 · Francine Grodstein, Bryan D James, et al. · The Journals of Gerontology Series A · 11
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Limbic-predominant age-related TDP43 encephalopathy (LATE) neuropathological change in neurodegenerative diseases
2023 · Sukriti Nag, Julie A. Schneider · Nature Reviews Neurology · 62
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Measurement precision across cognitive domains in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) data set.
2023 · Paul K. Crane, Seo-Eun Choi, et al. · Neuropsychology · 19
Perceptions of Caring Recruitment Among Older Adults
2022 · Charlene J. Gamboa, Wrenetha A. Julion, et al. · Nursing Research · 3
Mood and activity changes during the COVID-19 pandemic in rural and urban Veterans and their cohabitants
2022 · Jack C. Lennon, Nathan Hantke, et al. · Clinical Gerontologist · 6
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Cognitive decline and hippocampal functional connectivity within older Black adults
2022 · S. Duke Han, Debra A. Fleischman, et al. · Human Brain Mapping · 12
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Decision Making and Blood Sugar Indicators in Older African American Adults
2022 · Veronica Eloesa McSorley, Melissa Lamar, et al. · Journal of Aging and Health · 2
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Cognitive domain harmonization and cocalibration in studies of older adults.
2022 · Shubhabrata Mukherjee, Seo-Eun Choi, et al. · Neuropsychology · 105
The Relationship of John Henryism With Cognitive Function and Decline in Older Black Adults
2022 · Veronica Eloesa McSorley, Christopher Howard, et al. · Psychosomatic Medicine · 6
Social Engagement and All-Cause Mortality: A Focus on Participants of the Minority Aging Research Study
2022 · Melissa Lamar, Bryan D. James, et al. · American Journal of Preventive Medicine · 22
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