COcoa Supplement and Multivitamins Outcomes Study (COSMOS): Effects on Falls and Physical Performance
Description: PROJECT NARRATIVE Cocoa products, containing high concentrations of flavanols, are widely used and their health benefits have received increasing attention in the medical literature. Promising results from preclinical and clinical studies show beneficial effects of flavanols on muscle and physical performance, but no large, randomized controlled trials have tested effects of supplemental cocoa flavanols on clinically meaningful outcomes among aging adults. This study will determine whether supplemental cocoa flavanols slow age-related declines in physical performance and decrease falls and fall-related fractures (broken bones) that are major public health problems in older women and men in the U.S.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2021-05-15
End date: 2026-02-28
Investigator: CAROLYN JANET CRANDALL
Institution: BRIGHAM AND WOMEN'S HOSPITAL
Funded outputs count: 40
Funder award ID: R01AG071611
OpenAlex ID: G3555371772