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Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-Up

Description: PROJECT NARRATIVE We are reapplying to include the Wisconsin Infant Study Cohort (WISC), involving a critical rural underserved population, in the next phase of the Environmental Influences on Child Health Outcomes (ECHO) program. Our area of specialization within ECHO is upper and lower airway disease. We propose innovative studies focusing on how early life factors interact with airway epithelial cells to promote asthma onset and persistence.
Funding type: cooperative_agreement
Funder scheme: UG3
Start date: 2016-09-21
End date: 2025-05-31
Investigator: JAMES E. GERN
Institution: UNIVERSITY OF WISCONSIN-MADISON
Subfield: Physiology
Field: Medicine
Funded outputs count: 156
Funder award ID: UG3OD023282
OpenAlex ID: G1281777822
Exploratory integrative analysis of infant gut microbiome and metabolome suggests diet- and microbiome-derived metabolites associated with childhood asthma
2026 · Kedir N. Turi, Xiliu Wu, et al. · Metabolomics
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Early-life wheezing and childhood cognition in the ECHO cohort
2026 · Sima K. Ramratnam, Susan Korrick, et al. · Journal of Allergy and Clinical Immunology
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Dietary guidelines adherence and pregnancy exposure to 10 classes of priority chemicals: an observational study in the Environmental influences on Child Health Outcomes Cohort
2026 · Diana C Pacyga, Xiaoshuang Xun, et al. · American Journal of Clinical Nutrition · 1
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Prenatal Exposure to Nitrogen Dioxide, Fine Particulates, and Ozone in Relation to Child Behavior: The Environmental Influences on Child Health Outcomes Cohort
2026 · Jiwon Oh, Akhgar Ghassabian, et al. · Environmental Science & Technology · 1
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Prenatal exposure to gas stoves, mold, and water damage: Associations with gestational duration and fetal growth in the ECHO cohort
2026 · Jiwon Oh, Lesliam Quirós-Alcalá, et al. · Environmental Pollution · 1
Genome-wide association study of asthma with high treatment burden and/or worse outcomes defined using electronic healthcare data in UK Biobank
2026 · Noemi N. Piga, Michael A. Portelli, et al. · ERJ Open Research
Fast and reliable association discovery in large-scale microbiome studies and meta-analyses using PALM
2026 · Zhoujingpeng Wei, Qilin Hong, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
Per- and Polyfluoroalkyl Substances During Pregnancy and Gestational Diabetes: The Environmental Influences on Child Health Outcomes (ECHO) Cohort
2026 · Anne P. Starling, Mohamad Burjak, et al. · Diabetes Care
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Gestational exposure to organophosphate ester flame retardants and child growth in weight, height, and body mass index at age 2-10 years: the Environmental influences on Child Health Outcomes Program
2026 · Anne P. Starling, Xuan Li, et al. · Environmental Research
Infant Infection With Respiratory Syncytial Virus Genotypes and Subsequent Childhood Asthma Risk
2026 · Christian Rosas-Salazar, Tebeb Gebretsadik, et al. · The Journal of Infectious Diseases · 1
Placental histopathology and early childhood neurodevelopment in the Environmental influences on Child Health Outcomes cohort
2026 · Stephanie A. Fisher, Xiaoshuang Xun, et al. · American Journal of Obstetrics and Gynecology · 1
Predicting age of respiratory syncytial virus infection from birth timing
2026 · Chris G. McKennan, Tebeb Gebretsadik, et al. · Nature Communications
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Pre- and postnatal exposure to PM2.5 and NO2 and blood pressure in children: Results from the ECHO Cohort
2025 · Yu Ni, Andrew Law, et al. · Environmental Research · 1
Gestational fine particulate matter exposure and perinatal outcomes in the ECHO cohort: Associations across pregnancy windows
2025 · Adaeze W. Nzegwu, Aisha S. Dickerson, et al. · Environmental Research · 2
Vaginal microbiome structure in pregnancy and host factors predict preterm birth: Results from the ECHO Cohort
2025 · Kimberly S. McKee, Christine M. Bassis, et al. · Annals of Epidemiology · 5
Associations between body weight, asthma burden, and type 2 inflammation among under-resourced children
2025 · David Thompson, Cynthia M. Visness, et al. · Annals of Allergy Asthma & Immunology · 2
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Association between prenatal exposures to per- and polyfluoroalkyl substances and early language development in the ECHO cohort
2025 · Patricia Cintora, Lesliam Quirós-Alcalá, et al. · NeuroToxicology
Association of Maternal Prepregnancy BMI With Offspring Cardiometabolic Outcomes in Childhood
2025 · Rachana Singh, Christopher B. Pierce, et al. · Obesity · 1
Prenatal exposure to per- and polyfluoroalkyl substances: Association with child behavior in the environmental influences on child health outcomes (ECHO) Cohort
2025 · Catherine M. Bulka, Lesliam Quiros-Alcala, et al. · Environment International · 3
The Common Cold Is Associated With Protection From SARS-CoV-2 Infections
2025 · Camille M Moore, Elizabeth A Secor, et al. · The Journal of Infectious Diseases · 11
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Impact of nasal and inhaled corticosteroids on SARS-CoV-2 infection susceptibility
2025 · Christian Rosas-Salazar, Tebeb Gebretsadik, et al. · Journal of Allergy and Clinical Immunology
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Assessing cognition in autistic youth with and without attention‐deficit/hyperactivity disorder using the NIH Toolbox Cognition Battery: An Environmental influences on Child Health Outcomes‐Wide Cohort Study
2025 · Catrina A. Calub, Aisha S. Dickerson, et al. · JCPP Advances
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Prenatal exposure to phthalates and alternative plasticizers and emotional and behavioral outcomes in early childhood in the Environmental influences on Child Health outcomes (ECHO) cohort
2025 · Jiwon Oh, Jessie P. Buckley, et al. · Environment International · 2
Prenatal exposure to organophosphate ester flame retardants and behavioral outcomes in early childhood in the Environmental influences on Child Health Outcomes (ECHO) cohort
2025 · Jiwon Oh, Lesliam Quirós-Alcalá, et al. · Environment International · 6
Genetic contributions to epigenetic-defined endotypes of allergic phenotypes in children
2025 · Emma E. Thompson, Xiaoyuan Zhong, et al. · The American Journal of Human Genetics · 7
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