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AG056278

Funded outputs count: 62
Funder award ID: AG056278
OpenAlex ID: G9000047526
Mouse Cardiac Regeneration Database (MCAREDB): a single-cell atlas of neonatal cardiac regeneration in mice
2026 · Anthony Shea, Jiayi Cui, et al. · Scientific Reports
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Novel Flavonoid Senotherapeutics Identified by Phenotypic Drug Discovery Reduce Senescence and Improve Multiple Markers of Healthspan
2026 · Lei Justan Zhang, Rahagir Salekeen, et al. · Aging Cell
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Tomatidine is a senotherapeutic compound that improves cognitive function and reduces cellular senescence in aged mice
2026 · Daniela G Costa, Lucy M Gee, et al. · EMBO Molecular Medicine · 6
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High cancer-associated mutational burden in normal blood of xeroderma pigmentosum group C, but not groups A, D, or F
2026 · Gordon Fan-Huang, Elizabeth L. Schmidt, et al. · Blood Neoplasia
Slowing intervertebral disc aging in mice through long-term systemic treatment with the senolytic BCL-2/BCL-xL proteolysis targeting chimera (PROTAC) 753b
2026 · Peter G. Alexander, Bowen Yan, et al. · Aging · 1
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Genetic links between multimorbidity and human aging
2025 · Phuong-Anh Dinh, HyeRim Han, et al. · GeroScience · 4
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Space radiation induces distinct senescent phenotypes: Implications for space travel
2025 · Louise E. Pitcher, Bipasha Mukherjee, et al. · npj Aging · 4
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SomaMutDB 2.0: A comprehensive database for exploring somatic mutations and their functional impact in normal human tissues
2025 · Anthony Shea, Shixiang Sun, et al. · Nucleic Acids Research · 1
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Human Cell Aging Transcriptome Atlas (HCATA): a single-cell atlas of age-associated transcriptomic alterations across human tissues
2025 · Josh Bartz, Xiao Ma, et al. · Communications Biology · 3
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A benchmark of the somatic mutation landscape using single-cell and single-molecule whole-genome sequencing
2025 · Jacob E. Bridge, Chuwei Xia, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Identification of miR-106b-5p as a senolytic miRNA
2025 · Tianpeng Zhang, Allancer Nunes, et al. · EBioMedicine · 3
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Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair
2025 · Paul Robbins, Lei Zhang, et al. · Research Square · 5
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Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair
2025 · Lei Justan Zhang, Osama Elsallabi, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Identification of Senomorphic miRNAs in Embryonic Progenitor and Adult Stem Cell‐Derived Extracellular Vesicles
2025 · Tianpeng Zhang, Allancer D. C. Nunes, et al. · Aging Cell · 10
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Attenuation of Cellular Senescence and Improvement of Osteogenic Differentiation Capacity of Human Liver Stem Cells Using Specific Senomorphic and Senolytic Agents
2025 · Allancer D. C. Nunes, Louise E. Pitcher, et al. · Stem Cell Reviews and Reports · 1
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Biological sex matters in brain aging
2025 · Dena B. Dubal, Coleen T. Murphy, et al. · Neuron · 20
The Fifth Annual Symposium of the Midwest Aging Consortium
2024 · Brenda F Reader, Lorena Rosas, et al. · The Journals of Gerontology Series A
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Polygenic prediction of human longevity on the supposition of pervasive pleiotropy
2024 · M. Reza Jabalameli, Jhih-Rong Lin, et al. · Scientific Reports · 3
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A nutrigeroscience approach: Dietary macronutrients and cellular senescence
2024 · Mariah F. Calubag, Paul D. Robbins, et al. · Cell Metabolism · 31
Aging of the eye: Lessons from cataracts and age-related macular degeneration
2024 · Ales Cvekl, Jan Vijg · Ageing Research Reviews · 72
Developing transcriptomic signatures as a biomarker of cellular senescence
2024 · Shamsed Mahmud, Louise E. Pitcher, et al. · Ageing Research Reviews · 32
Negative Selection Allows DNA Mismatch Repair-Deficient Mouse Fibroblasts In Vitro to Tolerate High Levels of Somatic Mutations
2024 · Lei Zhang, Moonsook Lee, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
A systems biology-based identification and in vivo functional screening of Alzheimer’s disease risk genes reveal modulators of memory function
2024 · Adam D. Hudgins, Shiyi Zhou, et al. · Neuron · 3
Somatic mutations in aging and disease
2024 · Peijun Ren, Jie Zhang, et al. · GeroScience · 29
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Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia
2023 · Davis A. Englund, Alyssa M. Jolliffe, et al. · JCI Insight · 35
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