Neuroimmune Mechanisms of Cognitive Impairment in Salt-sensitive Hypertension
Description: PROJECT NARRATIVE Hypertension is a leading risk factor for cognitive impairment and dementia, a condition affecting almost 50 million adults worldwide, and a major cause of death and disability. This application seeks to determine the mechanisms underlying the damaging effects of hypertension on the brain by focusing on salt-sensitivity and immune signaling, key features of human hypertension. By identifying the molecules and cells involved in the harmful effects of hypertension on the brain, our studies have the potential to provide novel therapeutic insights to protect the brain from the effects of high blood pressure.
Funding type: career_development
Funder scheme: K22
Start date: 2021-07-15
End date: 2026-07-31
Investigator: MONICA M SANTISTEBAN FREEMAN
Institution: VANDERBILT UNIVERSITY MEDICAL CENTER
Funded outputs count: 9
Funder award ID: K22NS123507
OpenAlex ID: G9000858002