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AG-32576

Funded outputs count: 27
Funder award ID: AG-32576
OpenAlex ID: G9000052191
Immunometabolic effects of lactate on humoral immunity in healthy individuals of different ages
2024 · Maria Romero, Kate Miller, et al. · Nature Communications · 38
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Adipocyte‐derived inflammatory molecules induce senescent B cells through metabolic pathways
2024 · Daniela Frasca, Maria Romero, et al. · Obesity · 8
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Immunometabolic effects of lactate on B cell function in healthy individuals of different ages
2023 · Maria Romero, Kate Miller, et al. · medRxiv · 4
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Obesity accelerates age defects in B cells, and weight loss improves B cell function
2023 · Daniela Frasca, Maria Romero, et al. · Immunity & Ageing · 35
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Several areas of overlap between obesity and aging indicate obesity as a biomarker of accelerated aging of human B cell function and antibody responses
2022 · Daniela Frasca · Immunity & Ageing · 25
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Obesity Accelerates Age-Associated Defects in Human B Cells Through a Metabolic Reprogramming Induced by the Fatty Acid Palmitate
2022 · Daniela Frasca, Maria Romero, et al. · Frontiers in Aging · 27
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The majority of SARS-CoV-2-specific antibodies in COVID-19 patients with obesity are autoimmune and not neutralizing
2021 · Daniela Frasca, Lisa Reidy, et al. · International Journal of Obesity · 55
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Metformin Enhances B Cell Function and Antibody Responses of Elderly Individuals With Type-2 Diabetes Mellitus
2021 · Daniela Frasca, Alain Diaz, et al. · Frontiers in Aging · 44
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Influence of obesity on serum levels of SARS-CoV-2-specific antibodies in COVID-19 patients
2021 · Daniela Frasca, Lisa Reidy, et al. · PLoS ONE · 75
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Phenotypic and Functional Characterization of Double Negative B Cells in the Blood of Individuals With Obesity
2021 · Daniela Frasca, Alain Diaz, et al. · Frontiers in Immunology · 56
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B Cells with a Senescent-Associated Secretory Phenotype Accumulate in the Adipose Tissue of Individuals with Obesity
2021 · Daniela Frasca, Maria Romero, et al. · International Journal of Molecular Sciences · 43
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Effects of cellular senescence on metabolic pathways in non-immune and immune cells
2020 · Daniela Frasca, Yara Bou Saada, et al. · Mechanisms of Ageing and Development · 34
Aging induces B cell defects and decreased antibody responses to influenza infection and vaccination
2020 · Daniela Frasca, Bonnie B. Blomberg · Immunity & Ageing · 130
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Obesity Accelerates Age Defects in Mouse and Human B Cells
2020 · Daniela Frasca, Bonnie B. Blomberg · Frontiers in Immunology · 42
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Identification and Characterization of Adipose Tissue-Derived Human Antibodies With “Anti-self” Specificity
2020 · Daniela Frasca, Alain Diaz, et al. · Frontiers in Immunology · 38
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Influence of Obesity on Pneumococcus Infection Risk in the Elderly
2019 · Daniela Frasca, Janet McElhaney · Frontiers in Endocrinology · 56
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Secretion of autoimmune antibodies in the human subcutaneous adipose tissue
2018 · Daniela Frasca, Alain Diaz, et al. · PLoS ONE · 82
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Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells
2018 · Noémie Gensous, Claudio Franceschi, et al. · Experimental Gerontology · 24
Aging, Obesity, and Inflammatory Age-Related Diseases
2017 · Daniela Frasca, Bonnie B. Blomberg, et al. · Frontiers in Immunology · 371
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Adipose Tissue Inflammation Induces B Cell Inflammation and Decreases B Cell Function in Aging
2017 · Daniela Frasca, Bonnie B. Blomberg · Frontiers in Immunology · 66
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How does cytomegalovirus factor into diseases of aging and vaccine responses, and by what mechanisms?
2017 · Allison E. Aiello, Yen-Ling Chiu, et al. · GeroScience · 73
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Aging effects on T-bet expression in human B cell subsets
2017 · Daniela Frasca, Alain Diaz, et al. · Cellular Immunology · 63
Obesity decreases B cell responses in young and elderly individuals
2016 · Daniela Frasca, Franco Ferracci, et al. · Obesity · 228
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Aging, cytomegalovirus (CMV) and influenza vaccine responses
2015 · Daniela Frasca, Bonnie B. Blomberg · Human Vaccines & Immunotherapeutics · 46
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MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals
2015 · Daniela Frasca, Alain Diaz, et al. · The Journal of Immunology · 69
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